Results 71 to 80 of about 1,883,994 (277)
Background Refugees are at high risk for developing post-traumatic stress disorder (PTSD). Narrative exposure therapy (NET) is an evidence-based treatment of PTSD, designed for patients exposed to (multiple) traumatic events and recommended for patients
Simone M. de la Rie +5 more
doaj +1 more source
Probabilistic Nets-within-Nets
In this paper we study Hornets extended with firing probabilities. Hornets are a Nets-within-Nets formalism, i.e., a Petri net formalism where the tokens are Petri nets again. Each of these net-tokens has its own firing rate, independent from the rates of other net-tokens. Hornets provide algebraic operations to modify net-tokens during the firing. For
openaire +2 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
We design a new connectivity pattern for the U-Net architecture. Given several stacked U-Nets, we couple each U-Net pair through the connections of their semantic blocks, resulting in the coupled U-Nets (CU-Net). The coupling connections could make the information flow more efficiently across U-Nets.
Zhiqiang Tang 0001 +4 more
openaire +3 more sources
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The rapid development of open learning has seen a major change in the traditional tertiary student profile. Many new students have come to tertiary education with varying backgrounds that are often limited to less than three years of secondary schooling There has been a major change in the age and background profile of the New Zealand tertiary student ...
Nola Campbell +2 more
openaire +2 more sources

