Results 91 to 100 of about 16,571 (300)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Value Evaluation on Data Assets of P2P Net Loan Platform

open access: yesJournal of Physics: Conference Series, 2019
P2P net loan platform is the emerging force of economic development. The value evaluation on data assets of P2P net loan platform plays an important role in distinguishing the value of the data assets, providing a reference to improve the value of the data assets, and promoting the future development of the P2P platform.
Li Yonghong, Qin Kexin
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

PENGARUH PENGEMBALIAN ASET, RASIO UTANG TERHADAP ASET, PERTUMBUHAN PENJUALAN BERSIH, PERPUTARAN TOTAL ASET, DAN RASIO CEPAT TERHADAP NILAI PERUSAHAAN

open access: yesEquilibrium: Jurnal Ilmiah Ekonomi, Manajemen dan Akuntansi
ABSTRAKIndustri manufaktur semen merupakan salah satu elemen penting dalam perkembangan pembangunan nasional di Indonesia, karena memproduksi bahan pokok utama dalam membentuk pondasi dasar pembangunan infrastukur yang ada di Indonesia.
Yuannisa Aisanafi   +2 more
doaj   +1 more source

Rental Value of a Local Government Asset Using Asymmetric Valuation

open access: yesInternational Research Journal of Business Studies, 2019
This study tried to identified the market and the rental value of Grha Z as one of the local assets in Province A. This study used cost approach and income approach in valuation to obtain rental value and Net Present Value (NPV) of the building, the ...
Farach Difa   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Financial Investments in Romania. A Comparative Analysis between Open-end Mutual Funds and Bank Deposits [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2017
Despite the failures that investment funds have registered in Romania by the year 2000, they are a financial instrument chosen by more and more people to capitalize on their savings.
Pop Izabela Luiza, Hordău Anne Marie
doaj  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Asset-based measurement of poverty [PDF]

open access: yes
Poverty is generally defined as income or expenditure insufficiency, but the economic condition of a household also depends on its real and financial asset holdings.
Andrea Brandolini   +2 more
core  

ANALYTICS AND MODELING OF INVESTMENT ACTIVITY OF ENTERPRISES IN THE FIELD OF CAPITAL EXPENDITURES

open access: yesEkonomìčnij Vìsnik Nacìonalʹnogo Tehnìčnogo Unìversitetu Ukraïni "Kiïvsʹkij Polìtehnìčnij Institut"
This article explores the investment activity of Ukrainian enterprises, focusing on capital expenditures and their impact on asset value and net income.
Kateryna Boiarynova   +2 more
doaj   +1 more source

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