Results 121 to 130 of about 16,571 (300)
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
"How Far Can U.S. Equity Prices Fall Under Asset and Debt Deflation" [PDF]
Equity prices have been falling since March 2000. How far can they fall before they reach bottom? The current bear market differs from the mid-1970s plunge in equity prices in terms of the causes and, consequently, the factors that should be monitored to
E. Karakitsos, P. Arestis
core
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
, 2010 Company financial statements record and present all financial effects of transactions related to assets, capital, liabilities, expenses and revenues. These elements should reveal real flow of transactions in a company resulting in fair and objective presentation.
Anić-Antić, Paško, Ramljak, Branka
openaire +2 more sources
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Pengaruh Inflasi, Nilai Tukar Rupiah, BI Rate terhadap Net Asset Value Reksa Dana Saham Syariah
, 2015 This research aims to examine the influence of inflation, Rupiah exchange rate, and BI rate towards Net Asset Value (NAV) Sharia Equity Fund from January 2011 through December 2014. This research used the quantitative approach method.
Rachman, A. (Ainur), Mawardi, I. (Imron)
core
Net asset value discounts in listed private equity funds [PDF]
, 2009 This paper investigates determinants and consequences of net asset value discounts in listed private equity funds. Listed private equity funds share characteristics of closed-end mutual funds and traditional unlisted private equity funds and can ...
Lahr, Henry, Kaserer, Christoph
core
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
A Stochastic Linear Programming Model for Asset Liability Management: The Case of an Indian Insurance Company [PDF]
Asset - Liability management is one of the most critical tasks for any financial institution for determining its cushion against the risk and the net returns.
Basu Shankarshan +3 more
core