Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Project Report No. 46, Loblolly Pine Plantations in East Texas Two Harvest Schedules No Thinning & Final Harvest at 25 Years Thin at 10 Years & Final Harvest at 25 Years Sawlog/Veneer Wood Flow Comparison, A Simulation [PDF]
DOES A THINNING AT 10 YEARS WITH FINAL HARVEST AT 25 YEARS INCREASE SAWLOG/VENEER 1000 FLOW?
Allen, Jennifer, Lenhart, J. David
core +2 more sources
The Costs and Benefits of a Comprehensive Induction Program [PDF]
Until now there have been no benefit-cost studies of mentoring programs for beginning teachers to provide legislators, educational administrators, and program leaders with the kind of economic information they need for informed decision making.
Anthony Villar, Michael Strong
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Mastitis impact on high-yielding dairy farm's reproduction and net present value. [PDF]
Borş A, Borş SI, Floriștean VC.
europepmc +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Robust design of a logistics system using FePIA procedure and analysis of trade-offs between CO2 emissions and net present value. [PDF]
Roa AP, Escobar JW, Montoya MP.
europepmc +1 more source
Ethanol Plant Investment using Net Present Value and Real Options Analyses [PDF]
A real option analysis of dry-grind corn ethanol plants compared to a standard net present value analysis (NPV) shows that the option values increase entry prices and lower exit prices of investment and disinvestment considerably.
Luo, Jianchuan +2 more
core +1 more source

