Results 51 to 60 of about 1,830,042 (293)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

DETERMINANTS OF NET PROFIT MARGIN IN AICO ENERGY TECHNOLOGY, PT IN BALIKPAPAN

Jurnal Ekonomi dan Manajemen, 2021
This study aims to determine the low Net Profit Margin at Aico Energy Technology, PT in Balikpapan. The variable used is Net Profit Margin as the dependent variable, while the independent variables are Cash Turnover (X1), Accounts Receivable Turnover (X2), and Inventory Turnover (X3).
Anita De Grave, Syahril Hasan
openaire   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

THE INFLUENCE OF NET PROFIT MARGIN AND CURRENT RATIO ON STOCK PRICE

Jurnal Riset Akuntansi, 2017
 This research have purpose to examine empirically the effect on Net Profit Margin and Liquidity (Current Ratio) to Stock Price on Sub Sector Pharmaceutical Company Listed on IndonesiaStock Exchange Period 2012-2016. The problems that occur in Sub Sector Pharmaceutical Companyis the decrease of Stock Price but not followed by the increase of Net Profit
Anggadini, Sri Dewi, Tarsiah, Eva
openaire   +2 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Pengaruh Net Profit Margin (NPM) dan Operating Profit Margin (OPM) Terhadap Pertumbuhan Laba

Baashima : Jurnal Bisnis Digital, Akuntansi, Kewirausahaan, dan Manajemen
This study aims to determine and explain the influence of net profit margin (npm) and operating profit margin (OPM) on profit growth. The research method used is quantitative, with secondary data in the form of financial statements of PT. Matahari Department Store Tbk for the period of 2012-2022.
Alda Yulistiawati, Nurul Huda, Aris Munandar   +2 more
openaire   +1 more source

The Effect of Current Ratio, Debt to Equity Ratio, Return On Assets, and Net Profit Margin on Profit Growth

Assets : Jurnal Ilmiah Ilmu Akuntansi, Keuangan dan Pajak, 2022
This study aims to empirically test the effect of the Current Ratio, Debt to Equity Ratio, Return On Assets, and Net Profit Margin on Profit Growth. The population used is the consumer goods sector companies listed on the IDX in 2016-2020. Sample selection using purposive sampling method.
Anny Widiasmara, Agiesti Kusherawati, Retno Cahyaningati, Ratna Wijayanti Daniar Paramita   +3 more
openaire   +1 more source

Kinerja Akuisisi Industri Semen di Indonesia Tahun 2009 – 2013 [The Performance of Cement Industry Acquisitions in Indonesia 2009 – 2013]

DeReMa (Development Research of Management): Jurnal Manajemen, 2017
This research tried to explore the long term financial performance (window period = 3 years) after aquisitions in the cement industry during the period 2009–2013.
Imelda Imelda, Rina Adi Kristianti
doaj   +1 more source

PENGARUH DEBT TO EQUITY RATIO, CURRENT RATIO DAN NET PROFIT MARGIN TERHADAP PERTUMBUHAN LABA PERUSAHAAN YANG TERDAFTAR DI INDEKS LQ-45 BURSA EFEK INDONESIA

Kompartemen: Jurnal Ilmiah Akuntansi, 2022
Penelitian ini bertujuan untuk mengetahui pengaruh debt to equity ratio, current ratio dan net profit margin terhadap pertumbuhan laba perusahaan. Jenis Penelitian ini adalah kuantitatif dengan pendekatan deskriptif.
Nur Amalina, Adi Rizfal Efriadi
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source