Results 161 to 170 of about 6,776,297 (295)

Non‐Covalent Reversibly Photoconvertible Fluorescent Tags for Wash‐Free Protein Labeling

Advanced Science, EarlyView.
FAST proteins combined with one or two fluorogens undergo reversible fluorescence switching or photoconversion through photoisomerization. At low fluorogen concentration and high light intensity, they act as negative or positive photoswitchers and photoconvertible tags, which are promising for discriminating FAST variants.
Mrinal Mandal, Yuriy Shpinov, Aliénor Lahlou, Fivos Pham, Lina El Hajji, Ian Coghill, Eve Laureau, Marie‐Aude Plamont, Franck Perez, Thomas Le Saux, Isabelle Aujard, Arnaud Gautier, Ludovic Jullien   +12 more
wiley   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

Advanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li, Jiayi Li, Ang Dong, Xiaoyan Guo, Qiuyue Tu, Zelin Feng, Haojia Lin, Yanru Zhang, Yuxuan Hao, Huiying Gong, Yihan Meng, Yu Wang, Shing‐Tung Yau, Xiaocang Cao, Rongling Wu, Xinjuan Liu   +15 more
wiley   +1 more source

Soil pH Amelioration Synergizes Carbon Accrual with Yield Gains Under Organic Substitution

Advanced Science, EarlyView.
Soil pH shifts towards neutrality in both acidic and alkaline soils under organic substitution. A global synthesis links pH amelioration to soil organic carbon accrual through enhanced microbial biomass after accounting for added organic carbon and its interaction with pH. This pH amelioration‐shared soil organic carbon accrual accounts for 5.1–8.6% of
Xunzhuo Dong, Yanzhong Yao, Bingbing Han, Yunyao Zhong, Benyi Li, Mengfei Li, Yunchao Dai, Zhaolei Li   +7 more
wiley   +1 more source

PBRM1 Deficiency in Microglia Leads to Excessive Neurogenesis and Autism‐Like Behaviors via the CCL5‐CCR1/5‐β‐catenin Signaling Axis

Advanced Science, EarlyView.
Microglial PBRM1 deficiency drives excessive hippocampal neurogenesis by enhancing CCL5–CCR1/5 signaling, leading to autism‐like behaviors. A pro‐inflammatory IL1α+/TNFα+ microglial subset is identified as a key cellular contributor to this process. PBRM1 represses Ccl5 expression at the transcriptional level.
Yang‐Yang Duan, Lin‐Fei Jiao, Pei‐Pei Liu, Chun‐Hui Duan, Xiao Li, Zi‐Han Zhang, Yue‐Qi Zhang, Xin‐Li Ouyang, Hong‐Zhen Du, Sha Liu, Yi Tang, Zhao‐Qian Teng, Chang‐Mei Liu   +12 more
wiley   +1 more source

Bacteria‐Derived 1‐Allylpiperazine Alleviates Symptoms of Parkinson's Disease Model by Promoting Autophagy

Advanced Science, EarlyView.
Parkinson's disease currently has no disease‐modifying therapies. In Caenorhabditis elegans, Escherichia coli E8 alleviates α‐synuclein‐provoked PD‐related defects through its bioactive metabolite 1‐ALPP, which combats PD by triggering AMPK/mTOR/HLH‐30‐dependent autophagy and suppressing α‐synuclein LLPS‐mediated fibrillization.
Mingqin Qu, Xinyuan Zhang, Xinyi Chen, Jiaxin Shi, Meng Xu, Fuhao Wang, Jinling Lv, Jiaman Sun, Weiyi Niu, Zihan Liu, Li Li, Fufeng Liu, Xiangming Wang   +12 more
wiley   +1 more source

ANALISIS PENGARUH NET WORKING CAPITAL DAN NET PROFIT MARGIN TERHADAP GROWTH RATIO PADA PERUSAHAAN INDUSTRI DASAR DAN KIMIA YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2012 DAN 2013

, 2015
Pada umumnya sebuah perusahaan didirikan dengan tujuan untuk memperoleh laba yang optimal dari modal yang diinvestasikan, atau untuk mencapai laba yang maksimal dengan meningkatkan pendapatan dan menekan biaya.
B51111027, Suyenni
core  

LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening

Advanced Science, EarlyView.
LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico, Sara Rigolli, Julius Zimmermann, Melissa Pezzotti, Eloisa Torchia, Moises Di Sante, Ferdinando Auricchio, Francesco S. Pasqualini   +7 more
wiley   +1 more source

The Impacts of Changes in Macro-Economic Data on Net Working Capital: The Case of Turkey's Industrial Sector

, 2016
Ability to pay of a company's short term liabilities is closely related to its strong liquidity structure. One of the most important factors affecting the liquidity of a company is operating cycle.
Çelik, Reşit, Bilen, Ömer, Bilen, Bahar   +2 more
core  

Transforming Gas Separations with Scalable Carbon Molecular Sieve Membranes Enabled by Chemically Tuned Hollow‐Fiber Precursors

Advanced Science, EarlyView.
We established a broadly tunable network‐polymer platform for polyimide‐based precursor membranes, extendable to various diamines. Ultrahigh selectivity with demonstrated aging resistance, and scalability via hollow fiber CMS engineering collectively establishes broad and lasting impact for the membrane science and engineering communities.
Yuhe Cao, Zhongyun Liu, Zahra Shomali, Jinyoung Kim, Steven Schlosser, Ryan P. Lively, William J. Koros   +6 more
wiley   +1 more source

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

Advanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin, Sisi Chen, Shengli Huang, Mengqi Huang, Jingyan Zhu, Zijian Wang, Jianliang Shen, Qinxiang Zheng   +7 more
wiley   +1 more source