Results 151 to 160 of about 223,350 (308)

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Rapid synthesis: Achieving net-zero emissions in health systems through strategic funding partnerships and networks

open access: yes
An in-depth synthesis of what is known based on the best available global research evidence (i.e., evidence syntheses) and local research evidence (i.e., single studies) and may include a scan of experiences from other countries and from Canadian ...
Jaspal, A   +5 more
core  

Assessing global cities' climate policy with self-reported pledges, plans & targets on net-zero transition

open access: yes
With the accelerated global momentum towards a net zero economy, cities are increasingly serving as agents of decarbonisation and setting ambitious climate targets.
Ling, Chester Yuxuan
core  

Sharing the effort: Annual Net-Zero Report 2024 [PDF]

open access: yes
Countries around the world have committed to reducing greenhouse gas (GHG) emissions in line with the Paris Agreement’s goal of ‘limiting global temperature rise to well below 2 °C and pursue efforts to limit it to 1.5 °C’ (UNFCCC, 2015a).
Dafnomilis, I.   +11 more
core  

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

A review of net-zero greenhouse gas (GHG) emission non-regulatory environmental building standards and frameworks

open access: yes
Non-regulatory environmental building standards have been used in the built environment for more than thirty years and have had considerable influence over building development and policy.
Robertson, Craig   +3 more
core   +1 more source

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles   +14 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

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