Results 61 to 70 of about 1,663,813 (295)
EnergiesThis paper evaluates a Sustainable Energy Efficiency Business Model (SEEBM) for small and medium sized enterprises (SMEs) in the European industrial sector.
Usain Kadri +3 more
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
States of Local Moment Induced by Nonmagnetic Impurities in Cuprate Superconductors [PDF]
, 2003 By using a model Hamiltonian with d-wave superconductivity and competing antiferromagnetic (AF) orders, the local staggered magnetization distribution due to nonmagnetic impurities in cuprate superconductors is investigated.
Chen, Yan, Ting, C. S.
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Market transformations: gas conversion as a blueprint for net zero retrofit
Buildings & CitiesAll UK net zero scenarios call for zero gas use in homes by 2050. Delivering this along with any enabling measures is the largest heating market transformation since the gas conversion in the period 1965–77.
Aaron Gillich
doaj +1 more source
Efficient Elastic Net Regularization for Sparse Linear Models [PDF]
, 2015 This paper presents an algorithm for efficient training of sparse linear models with elastic net regularization. Extending previous work on delayed updates, the new algorithm applies stochastic gradient updates to non-zero features only, bringing weights
Elkan, Charles, Lipton, Zachary C.
core
Decarbonizing development: three steps to a zero-carbon future [PDF]
, 2015 This report lays out three steps for a smooth transition to a zero-carbon future and provides data, examples and policy advice to help countries makes the shift. Overview Getting to zero net emissions and stabilizing climate change starts with planning
Adrien Vogt-Schilb +5 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Beam-Energy and System-Size Dependence of Dynamical Net Charge Fluctuations
, 2008 We present measurements of net charge fluctuations in $Au + Au$ collisions at $\sqrt{s_{NN}} = $ 19.6, 62.4, 130, and 200 GeV, $Cu + Cu$ collisions at $\sqrt{s_{NN}} = $ 62.4, 200 GeV, and $p + p$ collisions at $\sqrt{s} = $ 200 GeV using the net charge ...
B. B. Back +7 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source