Results 211 to 220 of about 3,353,954 (329)
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah+9 more
wiley +1 more source
Small‐diameter vascular grafts with compliance tunable by design are fabricated via melt electrowriting. By controlling the winding angle of intertwined helical fibers, grafts with compliances matching those of human vessels, from veins to arteries, are realized. This holds the potential of avoiding a compliance mismatch, which has been identified as a
Kilian Maria Arthur Mueller+8 more
wiley +1 more source
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns+10 more
wiley +1 more source
Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Thomas Meslier+3 more
wiley +1 more source
Considering the full care pathway in regional variation in paediatric otitis media treatment in the Netherlands: an observational study. [PDF]
de Weerdt V+10 more
europepmc +1 more source
Social structure in the Western interior of Sarmi (Northern Netherlands New Guinea): a response to a response. (Zie nr. 1552) [PDF]
Jan Pouwer
openalex +1 more source
Readily UV‐curing and self‐healing methacrylated collagen peptide (COPMA) hydrogels are developed with tunable mechanical properties. As the interpenetrating network between COPMA and xanthan gum (XG), COPMA‐XG bioinks show improved mechanical properties, printability, and stability, compared to COPMA or XG.
Hongjuan Weng+6 more
wiley +1 more source
Development and Implementation of a Birth Forecasting Tool to Optimize Resources in Obstetrical Care During the COVID-19 Pandemic: Mixed-Methods Study. [PDF]
Joosse HJ+7 more
europepmc +1 more source