Results 241 to 250 of about 3,353,954 (329)

Environmental Policy Capacity Building in the Netherlands [PDF]

, 1995
Bressers, J.T.A., Plettenburg, L.A.
core   +1 more source

High‐Speed Raman Readout of Single Polypeptides via Plasmonic Nanopores

Advanced Materials, EarlyView.
A label‐free method is presented for single‐protein investigation using plasmonic nanopores that enable stable, cost‐effective Raman detection of polypeptides in real time. An average of 6 photons is measured during a dwell time of 7 microseconds per amino acid.
Foroogh Khozeymeh Sarbishe, Kirill Khabarov, Maria Blanco Formoso, Ilaria Micol Baldi, Veronica Storari, Henri Haka, Massimo Mastrangeli, Francesco Difato, Andrea Armirotti, Federica Villa, Francesco Tantussi, Francesco De Angelis   +11 more
wiley   +1 more source

A "Pandemic-Proof" Methodology for Outbreak Detection Adapted From COVID-19's Impact on Notifications of Infectious Diseases in the Netherlands: Surveillance Study.

JMIR Public Health Surveill
van Deursen B, Raven S, van den Bosch W, van Jaarsveld CHM, Timen A.   +4 more
europepmc   +1 more source

Perceptions on vaccines, vaccine communication and information needs of healthcare professionals involved in older adult vaccination: A cross-country interview study. [PDF]

PLOS Glob Public Health
Wennekes MD, De Haan F, Eilers R, Caputo A, Nicoli F, Nagy D, Stein ML, Gagneux-Brunon A, Gavioli R, Vokó Z, Timen A, VITAL Consortium.   +11 more
europepmc   +1 more source

Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells

Advanced Materials, EarlyView.
Apolipoprotein nanoparticle (aNP) platform technology efficiently delivers RNA to immune cells following systemic administration. Here, it is demonstrated that incorporating polyvalent ionizable cationic dendrimers in aNPs enables robust mRNA complexation and functional delivery.
Mirre M. Trines, Daniek Hoorn, Stijn R.J. Hofstraat, Robby C. Zwolsman, Tom Anbergen, Iris Versteeg, Yuri van van Elsas, Jeroen Deckers, Merel M.A. Hendrikx, Teun Kleuskens, Youssef B. Darwish, Gijs W.B. Ros, Sjoerd F. Dijkstra, Bram Priem, Matt Timmers, P. Michel Fransen, Maarten J. Pouderoijen, Bas F.M. de de Waal, E.W. Meijer, Thijs J. Beldman, Yohana C. Toner, Ewelina Kluza, Willem J.M. Mulder, Henk M. Janssen, Roy van der Meel   +24 more
wiley   +1 more source

Recombinant Myxoma Virus in European Brown Hares, 2023-2024. [PDF]

Emerg Infect Dis
Fischer L, de Bruin E, Jongepier E, Koffeman E, König P, Pfaff F, Peters M, van den Brand JMA, Bussi M, Fischer D, Caliendo V, Weerts E, IJzer J, Müller J, Kühling AK, Kummerfeld M, Müller J, Petersen H, Merbach S, Beer M, Uiterwijk M, de Boer K, Rijks JM.   +22 more
europepmc   +1 more source

MUTE‐Seq: An Ultrasensitive Method for Detecting Low‐Frequency Mutations in cfDNA With Engineered Advanced‐Fidelity FnCas9

Advanced Materials, EarlyView.
An advanced‐fidelity CRISPR nuclease, FnCas9‐AF2, is rationally engineered to discriminate single‐base mismatches with unprecedented level precision. Integrated into the MUTE‐Seq workflow, FnCas9‐AF2 depletes wild‐type cell‐free DNA, thereby exposing rare tumor‐derived mutant DNA (a molecular “needle in a haystack”).
Sunghyeok Ye, Jin‐Soo Kim, Myungshin Kim, Ki‐Yeon Kim, Yoon‐Ho Won, Taegun Park, Sungjae An, Haerin Jeong, Hee‐Joon Chung, In Seon Lee, Myoung‐Hee Kang, Chan Young Kang, Mi Young Kim, Jae Ho Chung, Jeong‐An Gim, Woochang Hwang, Yonggoo Kim, Song Cheol Kim, Sungho Lee, Junho K Hur, Junseok W Hur   +20 more
wiley   +1 more source

Interaction between coffee consumption and polygenic risk score in relation to diabetes: insights from the Maastricht study. [PDF]

Eur J Nutr
Rao Y, Yu EY, Lin TY, Chen Y, Qin Y, Koster A, Eussen SJPM, Bosma H, Berendschot TTJM, van der Kallen CJH, van Greevenbroek MMJ, de Galan BE, Zeegers MP, Wesselius A.   +13 more
europepmc   +1 more source

Micro‐Strain Responsive Near‐Infrared Mechanoluminescence for Potential Nondestructive Artificial Joint Stress Imaging

Advanced Materials, EarlyView.
In situ and real‐time stress sensing during total knee replacement procedure is expected to be realized based on near‐infrared mechanoluminescent phosphor of Sr3Sn1.98Sb0.02O6.99, which has the lowest strain sensitivity as low as 50 µst. Abstract Recently, joint replacement surgery is facing significant challenges of patient dissatisfaction and the ...
Wenhao Li, Puxian Xiong, Xiaoxin Zheng, Luyue Niu, Lugui Cui, Qingyu Wang, Bruno Viana, Pieter Dorenbos, Jianzhong Zhang, Jing Ren   +9 more
wiley   +1 more source

An Unexpected Case of Somatic Mosaicism of the Dutch p16-<i>Leiden</i> Founder Variant in the <i>CDKN2A</i> Gene. [PDF]

Case Rep Genet
van der Meulen M, van Wezel JT, Terlouw D, Morreau J, Steeghs EMP, van Doorn R, van Leerdam ME, Onnekink AM, de Ruiter MC, van der Stoep N, Potjer TP.   +10 more
europepmc   +1 more source