Results 101 to 110 of about 816,628 (364)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
On the discretized sum-product problem
, 2019 We give a new proof of the discretized ring theorem for sets of real numbers. As a special case, we show that if $A\subset\mathbb{R}$ is a $(\delta,1/2)_1$-set in the sense of Katz and Tao, then either $A+A$ or $A.A$ must have measure at least $|A|^{1 ...
Guth, Larry +2 more
core
A mixed-methods evaluation of transformational change in NHS North East
Health Services and Delivery Research, 2014 Background: The North East Transformation System (NETS) was conceived as an experiment in adopting large-scale transformational change across a NHS region in England.
David J Hunter +8 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Reviews of "Targeting Neutrophils Extracellular Traps (NETs) Reduces Multiple Organ Injury in a COVID-19 Mouse Model" [PDF]
, 2022 Teluguakula Narasaraju +1 more
openalex +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Review 1: "Targeting Neutrophils Extracellular Traps (NETs) Reduces Multiple Organ Injury in a COVID-19 Mouse Model" [PDF]
, 2022 Teluguakula Narasaraju
openalex +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Acta Arithmetica, 2014 The second author recently suggested to identify the generating matrices of a digital $(t,m,s)$-net over the finite field $F_q$ with an $s \times m$ matrix $C$ over $F_{q^m}$. More exactly, the entries of $C$ are determined by interpreting the rows of the generating matrices as elements of $F_{q^m}$.
Hofer, Roswitha, Niederreiter, Harald
openaire +2 more sources