Results 121 to 130 of about 816,628 (364)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Semantic Embedding of Petri Nets into Event-B

, 2005
We present an embedding of Petri nets into B abstract systems. The embedding is achieved by translating both the static structure (modelling aspect) and the evolution semantics of Petri nets.
Attiogbe, Christian
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Artificial Neural Nets and the Representation of Human Concepts [PDF]

, 2023
Timo Freiesleben
openalex   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Modeling and controlling IoT-based devices’ behavior with high-level Petri nets

, 2023
João Paulo da Silva Fonseca, Alexandre Rodrigues de Sousa, José Jean-Paul Zanlucchi de Souza Tavares   +2 more
openalex   +1 more source

Robustmix: Improving Robustness by Regularizing the Frequency Bias of Deep Nets [PDF]

, 2023
Jonas Ngnawé, Marianne ABEMGNIGNI NJIFON, Jonathan Heek, Yann Dauphin   +3 more
openalex   +1 more source

Empresarios de Los Andes de la colonia a la independencia: Dos estudios de casos de Jujuy

América Latina en la Historia Económica, 2009
El artículo estudia la trayectoria de dos empresarios de Jujuy entre la colonia y la temprana independencia: Manuel de Tezanos Pinto y Joseph de Alvarado.
Viviana Conti, Mirta Gutiérrez
doaj  

Influence of packing method on colour perception improving the appearance of fruits and vegetables

Research in Agricultural Engineering, 2008
The appearance of fruits and vegetables has a major influence on the perceived quality. Therefore, colour is one of the most important quality parameters in consumers' preferences.
B. Dobrzański, R. Rybczyński
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source