Results 121 to 130 of about 577,979 (302)
Blessed are the cheesemakers : evidence based policy versus the oral tradition [PDF]
, 2007 A paper presented at a special conference to celebrate the work of Brian Perry. Records the story of BLRDD and of research management in the UK from 1985-2000. Covers BLRDD, the Library and Information Commission and BLRIC.
Law, Derek
core +1 more source
Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices
Advanced Science, EarlyView.This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee +4 more
wiley +1 more source
The political economy of loose regulation: Modernity meets tradition in Hong Kong [PDF]
, 2007 Hong Kong is a fascinating social laboratory where one can observe the interplay between powerful forces of modernization and deeply-entrenched pre-industrial consumption patterns. For decades, the former had not encroached on the autonomy of grassroots-
Mushkat, M, Mushkat, R
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Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
wiley +1 more source
Working methodologically on system innovations [PDF]
, 2011 Dutch agriculture is facing the challenge to develop into a sustainable sector. To achieve this goal, innovations are needed which force breaks with past trends and speed up the tempo of sustainable development. The System Innovation Programmes developed
Vogelezang, J.V.M., Wijnands, F.G.
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Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Institutions, policy networks and agenda setting : heritage conservation in Hong Kong, 1970-1997
, 2012 published_or_final_version ; Politics and Public Administration ; Master ; Master of ...
openaire +2 more sources
Advanced Science, EarlyView.A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil +7 more
wiley +1 more source
A legacy handbook for enterprise [PDF]
, 2011 Legacy Handbook reviewing emda's experience of enterprise activity. Identifies key achievements and draws out lessons learned that may be relevant to successor bodies active in this ...
East Midlands Development Agency, EMDA
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Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model
Advanced Science, EarlyView.A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen +15 more
wiley +1 more source