Results 51 to 60 of about 577,979 (302)
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Background Precision public health is an emergent field that requires transdisciplinary collaborations and leverages innovative approaches to improve population health.
Caitlin G. Allen +7 more
doaj +1 more source
Policy forums: Why do they exist and what are they used for? [PDF]
Policy forums are issue-based intermediary organizations where diverse types of political and societal actors repeatedly interact. Policy forums are important elements of modern governance systems as they allow actors to learn, negotiate, or build trust.
Fischer, Manuel, Leifeld, Philip
core +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The Agenda-Setting Capacity of Global Networks
This chapter examines the agenda-setting capacity of global policy networks. It argues that the capacity of global networks to promote new ideas and understanding about issues at the global scale depends on their ability to produce information and indicators, to quantify the magnitude of issues and the consequences of inaction, and to take advantage of
openaire +2 more sources
Functional Connectivity Linked to Cognitive Recovery After Minor Stroke
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri +7 more
wiley +1 more source
This article investigates the third level of agenda setting during the anti–Moral and National Education movement in Hong Kong—a Chinese society—in the summer of 2012.
Yang Cheng, Ching-Man Chan
doaj
Throughout the COVID-19 crisis, as we confronted questions about social distancing, masking wearing, and vaccines, public safety experts warned that the consequences of a misinformed population would be particularly dire due to the serious nature of the
Masha Krupenkin +3 more
doaj +1 more source
Disaster risk management or adaptation to climate change; How to deal with climate issue in Colombia? Analysis from agenda setting and traveling model perspectives of the elaboration of climate policies. [PDF]
The main purpose of this work is to understand, in an actor oriented perspective, the context in which climate policy are formulated in a country, Colombia.
Howland, Fanny, Le Coq, Jean-François
core

