Results 1 to 10 of about 6,856,154 (215)

Impact of Sacubitril/Valsartan on Circulating microRNA in Patients with Heart Failure

Biomedicines, 2023
Sacubitril/Valsartan, used for the treatment of heart failure (HF), is a combination of two drugs, an angiotensin receptor inhibitor, and a neprilysin inhibitor, which activates vasoactive peptides. Even though its beneficial effects on cardiac functions
Maura Brioschi, Yuri D’Alessandra, Massimo Mapelli, Irene Mattavelli, Elisabetta Salvioni, Sonia Eligini, Alice Mallia, Veronica Ricci, Erica Gianazza, Stefania Ghilardi, Piergiuseppe Agostoni, Cristina Banfi   +11 more
doaj   +1 more source

Prenylcysteine Oxidase 1 Is a Key Regulator of Adipogenesis

Antioxidants, 2023
The process of adipogenesis involves the differentiation of preadipocytes into mature adipocytes. Excessive adipogenesis promotes obesity, a condition that increasingly threatens global health and contributes to the rapid rise of obesity-related diseases.
Cristina Banfi, Alice Mallia, Stefania Ghilardi, Maura Brioschi, Erica Gianazza, Sonia Eligini, Pelin Sahlén, Roberta Baetta   +7 more
doaj   +1 more source

Circulating brain-derived neurotrophic factor as a potential biomarker in stroke: a systematic review and meta-analysis

Journal of Translational Medicine, 2022
Background Stroke, an acute cerebrovascular event, is a leading cause of disability, placing a significant psycho-socioeconomic burden worldwide. The adaptation and reorganization process following any neuronal damage is regarded as neuroplasticity ...
Helia Mojtabavi, Zoha Shaka, Sara Momtazmanesh, Atra Ajdari, Nima Rezaei   +4 more
doaj   +1 more source

Leveraging human resources for outbreak analysis: lessons from an international collaboration to support the sub-Saharan African COVID-19 response

BMC Public Health, 2022
Emerging infectious diseases are a growing threat in sub-Saharan African countries, but the human and technical capacity to quickly respond to outbreaks remains limited.
Sara Botero-Mesa, Flavio Codeço Coelho, Kenechukwu Nwosu, Bertil Wicht, Akarsh Venkatasubramanian, Olena Wagner, Camille Valera, Benedict Nguimbis, Daniel Câmara, Izabel Reis, Lucas Bianchi, Morteza Mahdiani, Papy Ansobi Onsimbie, Papa Amadou Niang Diallo, Léa Jacques, Artur Manuel Muloliwa, Moussa Bougma, Leckson Mukavhi, Adit Kaneria, Ram Peruvemba, Ajay Gupta, Isotta Triulzi, Ananthu James, Verena Carrara, Wingston Ngambi, Zahra Habibi, Michael Tedros Adhanom, Sabina Rodriguez Velásquez, Paolo Sestito, Timokleia Kousil, Loza Biru, Daniela Vivacqua, Jyoti Dalal, Anatole Mian, Maroussia Roelens, Erol Orel, Cristina Barroso Hofer, Fatihiyya Wangara, Franck Mboussou, Tamayi Mlanda, Arish Bukhari, Theresa Min-Hyung Lee, Roland Ngom, Beat Stoll, Cleophas Chimbetete, Jessica Abbate, Benido Impouma, Olivia Keiser   +47 more
doaj   +1 more source

The Impact of Life Trajectories on Retirement: Socioeconomic Differences in Social Support Networks

Social Inclusion, 2021
In general, the literature about social support networks (SSNs) has been divided into two different statements: On the one hand, social support is a safety net that helps the ego confront disadvantages in life.
Francisca Ortiz, Elisa Bellotti
doaj   +1 more source

Albumin Thiolation and Oxidative Stress Status in Patients with Aortic Valve Stenosis

Biomolecules, 2023
Recent evidence indicates that reactive oxygen species play an important causative role in the onset and progression of valvular diseases. Here, we analyzed the oxidative modifications of albumin (HSA) occurring on Cysteine 34 and the antioxidant ...
Carlo Savini, Elena Tenti, Elisa Mikus, Sonia Eligini, Marco Munno, Anna Gaspardo, Erica Gianazza, Arianna Greco, Stefania Ghilardi, Giancarlo Aldini, Elena Tremoli, Cristina Banfi   +11 more
doaj   +1 more source

COVID-19 in Switzerland real-time epidemiological analyses powered by EpiGraphHub

Scientific Data, 2022
Here we present the design and results of an analytical pipeline for COVID-19 data for Switzerland. It is applied to openly available data from the beginning of the epidemic in 2020 to the present day (august 2022).
Flávio Codeço Coelho, Eduardo Corrêa Araújo, Olivia Keiser   +2 more
doaj   +1 more source

Impact of Experimental Conditions on Extracellular Vesicles’ Proteome: A Comparative Study

Life, 2023
Extracellular vesicle (EV) research is a rapidly developing field, mainly due to the key role of EVs in intercellular communication and pathophysiological processes.
Tímea Böröczky, Gabriella Dobra, Mátyás Bukva, Edina Gyukity-Sebestyén, Éva Hunyadi-Gulyás, Zsuzsanna Darula, Péter Horváth, Krisztina Buzás, Mária Harmati   +8 more
doaj   +1 more source

Reversibility of link prediction and its application to epidemic mitigation

Scientific Reports, 2022
Current link prediction strategies are about finding new probable strong relations to establish or weak ones to remove. An interesting strategy is utilizing link prediction to prioritize the edges in the network and finding newly probable established ...
Sadegh Sulaimany, Aso Mafakheri
doaj   +1 more source

N-acetylcysteine Amide AD4/NACA and Thioredoxin Mimetic Peptides Inhibit Platelet Aggregation and Protect against Oxidative Stress

Antioxidants, 2023
In the present study, we tested the effect of small-molecular-weight redox molecules on collagen-induced platelet aggregation. We used N-acetylcysteine amide (AD4/NACA), the amide form of N-acetylcysteine (NAC), a thiol antioxidant with improved ...
Sonia Eligini, Marco Munno, Daphne Atlas, Cristina Banfi   +3 more
doaj   +1 more source