Results 81 to 90 of about 2,214,703 (288)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Comparative efficacy, tolerability and safety of dolutegravir and efavirenz 400mg among antiretroviral therapies for first-line HIV treatment: A systematic literature review and network meta-analysis

, 2020
Steve Kanters, Marco Vitória, Michael J. Zoratti, Meg Doherty, Martina Penazzato, Ajay Rangaraj, Nathan Ford, Kristian Thorlund, Prof. Aslam H. Anis, Mohammad Ehsanul Karim, Lynne Mofenson, Rebecca Zash, Alexandra Calmy, Tamara Kredo, Nick Bansback   +14 more
openalex   +1 more source

A Comparative Study on the Effect of Welding Parameters of Austenitic Stainless Steels Using Artificial Neural Network and Taguchi Approaches with ANOVA Analysis [PDF]

, 2018
Halil İbrahim Kurt, Murat Oduncuoğlu, Necip Fazıl Yilmaz, Engin Ergül, Ramazan Asmatulu   +4 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Cross-Disciplinary Detection and Analysis of Network Motifs [PDF]

, 2015
Ngoc Tam Tran, Luke DeLuccia, Aidan McDonald, Chun-Hsi Huang   +3 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

An in-depth statistical analysis of the COVID-19 pandemic’s initial spread in the WHO African region

BMJ Global Health, 2022
Cristina Barroso Hofer, Benido Impouma, Olivia Keiser, Cleophas Chimbetete, Jyoti Dalal, Ananthu James, Sara Botero Mesa, Beat Stoll, Jessica Lee Abbate, Franck Mboussou, Flávio Codeço Coelho, Timokleia Kousi, Daniela Vivacqua, Daniel Cardoso Portela Câmara, Izabel Cristina Dos Reis, Wignston Ng’ambi, Papy Ansobi, Lucas M Bianchi, Theresa M Lee, Opeayo Ogundiran   +19 more
doaj   +1 more source

Immature Surfactant Protein Type B and Surfactant Protein Type D Correlate with Coronary Heart Disease in Patients with Type 2 Diabetes

Life
Background: Different specific surfactant proteins (SPs) have been associated with various pathological conditions, not only of the respiratory system, but also more recently with cardiovascular diseases, such as heart failure.
Cristina Banfi, Francesco Piarulli, Eugenio Ragazzi, Stefania Ghilardi, Arianna Greco, Annunziata Lapolla, Giovanni Sartore   +6 more
doaj   +1 more source

Evaluation of lattice curvature and crystalline homogeneity for 2-inch GaN homo-epitaxial layer

AIP Advances, 2018
We evaluated the lattice curvature, crystallinity, and crystalline homogeneity of a GaN layer on a free standing GaN substrate using lattice orientation measurements, θ rocking curves, and reciprocal space mapping from synchrotron X-ray diffraction ...
Okkyun Seo, Jae Myung Kim, Chulho Song, Yanfang Lou, L. S. R. Kumara, Satoshi Hiroi, Yanna Chen, Yoshio Katsuya, Yoshihiro Irokawa, Toshihide Nabatame, Yasuo Koide, Osami Sakata   +11 more
doaj   +1 more source