Results 81 to 90 of about 405,504 (268)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Beyond 5G. Strategic Pathways to 6G Development and Emerging Applications [PDF]

Iranian Journal of Information Processing & Management
Background: The rapid evolution from 4G to 5G has transformed the telecommunications landscape, but as technological demands continue to grow, the shift toward 6G is gaining attention.
Mohammed Abdul Jaleel Maktoof, Zaid Ghanim Ali, Azimov Bektur Abyrahmanovich, Ibraheem Mohammed Khalil, Waleed Nassar   +4 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Using individualized brain network for analyzing structural covariance of the cerebral cortex in Alzheimer’s patients

Frontiers in Neuroscience, 2016
Cortical thinning patterns in Alzheimer’s disease (AD) have been widely reported through conventional regional analysis. In addition, the coordinated variance of cortical thickness in different brain regions has been investigated both at the individual ...
Hee-Jong Kim, Hee-Jong Kim, Jeong-Hyeon Shin, Jeong-Hyeon Shin, Cheol E Han, Cheol E Han, Hee Jin Kim, Hee Jin Kim, Duk L. Na, Duk L. Na, Sang Won Seo, Sang Won Seo, Joon-Kyung Seong, Joon-Kyung Seong   +13 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Interconnection and coexistence of heterogeneous network:requirements, challenges, and architecture

Dianxin kexue, 2022
With the rapid development of the network technology and applications, many networks with different types of topologies and services have been emerging, such as Internet, satellite Internet, industrial Internet, unmanned aerial vehicle swarm network, and
Hongbin LUO, Shan ZHANG, Zhiyuan WANG
doaj  

The Collaboration for Content Delivery and Network Infrastructures: A Survey

IEEE Access, 2017
With the explosive growth of Internet traffic and the rapid development of network technology, content delivery has become a significant service in the current Internet.
Qingmin Jia, Renchao Xie, Tao Huang, Jiang Liu, Yunjie Liu   +4 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

A security architecture for personal networks [PDF]

, 2009
The proliferation of personal mobile computing devices such as laptops and mo- bile phones, as well as wearable computing devices such as belt computers, digital bracelets and bio-medical sensors has created an opportunity to create a wireless network to share information and resources amongst personal devices.
openaire   +2 more sources