Results 81 to 90 of about 876,573 (316)
Traffic Flow on a Road Network [PDF]
SIAM Journal on Mathematical Analysis, 2005 Summary: This paper is concerned with a fluid-dynamic model for traffic flow. More precisely, we consider a single conservation law, deduced from the conservation of the number of cars, defined on a road network that is a collection of roads with junctions.
Giuseppe Maria Coclite +2 more
openaire +5 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Phenotypes of Vascular Flow Networks [PDF]
Physical Review Letters, 2019 Complex distribution networks are pervasive in biology. Examples include nutrient transport in the slime mold \emph{Physarum polycephalum} as well as mammalian and plant venation. Adaptive rules are believed to guide development of these networks and lead to a reticulate, hierarchically nested topology that is both efficient and resilient against ...
Henrik Ronellenfitsch, Eleni Katifori
openaire +3 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Network-based IP flow mobility support in 3GPPs evolved packet core
, 2013 Includes bibliographical references.Mobile data traffic in cellular networks has increased tremendously in the last few years. Due to the costs associated with licensed spectrum, Mobile Network Operators (MNOs) are battling to manage these increased ...
John, Charna Tina
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Reactive/Adsorptive transport in (partially-) saturated porous media: from pore scale to core scale
, 2011 Pore-scale modeling provides opportunities to study transport phenomena in fundamental ways because detailed information is available at the microscopic pore scale. This offers the best hope for bridging the traditional gap that exists between pore scale
Raoof, A. +2 more
core
Minimum Link Flow Problem and Its Solution With Sparse Modeling
IEEE AccessRecently, a statistical modeling approach called sparse modeling has attracted much attention, especially in the fields of signal and image processing.
Ryotaro Matsuo +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source