Results 81 to 90 of about 8,372,639 (310)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Guessing numbers based on network routing capacity [PDF]
, 2009 In this thesis, a new method of studying problems in network information flow is introduced. This is established by developing on the relatively new concept of guessing numbers, which is related to network coding, and combining it with another technique ...
Buckley, Christopher
core
Minimum Link Flow Problem and Its Solution With Sparse Modeling
IEEE AccessRecently, a statistical modeling approach called sparse modeling has attracted much attention, especially in the fields of signal and image processing.
Ryotaro Matsuo +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
MathematicsNetwork flow task management involves the efficient allocation and scheduling of data flow tasks within dynamic satellite networks, aiming to effectively address frequent changes in network topology and dynamic traffic fluctuations.
Shangpeng Wang +4 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Graph-based strategies for optimising wildfire suppression
Journal of Physics: ComplexityWe present an algorithm for wildfire suppression based on graph theory that builds on realistic simulations of the propagation, is efficient, produces results in a short time, and has the potential to help achieve a faster suppression of a real fire. The
J Aveiro +7 more
doaj +1 more source
The maximum flow in dynamic networks [PDF]
Computer Science Journal of Moldova, 2005 The dynamic maximum flow problem that generalizes the static maximum flow problem is formulated and studied. We consider the problem on a network with capacities depending on time, fixed transit times on the arcs, and a given time horizon.
Maria A. Fonoberova, Dmitrii D. Lozovanu
doaj
Network Flow Classification Methodrule-Based
Journal of Harbin University of Science and Technology, 2017 In this paper，repeated incremental pruning to produce error reduction which is a rule learning ethod is used to solve network traffic classification. The method can be used to dig out the correlations between ttributes and classes，which are utilized to ...
CAO Yan-zhen +3 more
doaj +1 more source