Results 151 to 160 of about 120,423 (316)
Semantic social network analysis foresees message flows
Social Network Analysis is employed widely as a means to compute the probability that a given message flows through a social network. This approach is mainly grounded upon the correct usage of three basic graph-theoretic measures: Degree centrality ...
Matteo Cristani +8 more
core +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
A continuous network design model in stochastic user equilibrium based on sensitivity analysis
The continuous network design problem (CNDP) is known to be difficult to solve due to the intrinsic properties of non-convexity and nonlinearity. Such kinds of CNDP can be formulated as a bi-level programme, in which the upper level represents the ...
Lim, Yongtaek +5 more
core
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +2 more
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Removing Undesirable Flows by Edge Deletion
Consider mitigating the effects of denial of service or of malicious traffic in networks by deleting edges. Edge deletion reduces the DoS or the number of the malicious flows, but it also inadvertently removes some of the desired flows.
Trajanovski, S. +6 more
core +1 more source
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Special structure linear programming problems have received considerable attention during the last two decades and among them network problems are of particular importance and have found numerous applications in manage- ment science and technology.
Djannaty, F, Dowman, KD
core
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source

