Results 51 to 60 of about 914,936 (268)

Statistical Traffic State Analysis in Large-scale Transportation Networks Using Locality-Preserving Non-negative Matrix Factorization [PDF]

, 2012
Statistical traffic data analysis is a hot topic in traffic management and control. In this field, current research progresses focus on analyzing traffic flows of individual links or local regions in a transportation network.
Han, Yufei, Moutarde, Fabien
core   +5 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Flow characteristics in flow networks [PDF]

Experiments in Fluids, 1993
A flow network is a system of mutually intersecting holes in a plate or an assembly of plates. The flow at each intersection is characterized by a collision of two flow streams, resulting in complex flow patterns through the downstream holes. In the case of multiple intersections, the flow is periodically disrupted at each succeeding intersection, thus
Lee, C. P., Zhang, N., Yang, Wen-Jei, Xu, Y.   +3 more
openaire   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

SELECTED ISSUES IN MODELLING OF TRAFFIC FLOWS IN CONGESTED URBAN [PDF]

Archives of Transport, 2014
Making rational decisions about the planning and designing the traffic management in the city requires a proper description of traffic flows following through the various elements of the transportation network.
Renata Żochowska
doaj   +1 more source

Counting Integer Flows in Networks [PDF]

Foundations of Computational Mathematics, 2004
This paper discusses new analytic algorithms and software for the enumeration of all integer flows inside a network. Concrete applications abound in graph theory \cite{Jaeger}, representation theory \cite{kirillov}, and statistics \cite{persi}. Our methods clearly surpass traditional exhaustive enumeration and other algorithms and can even yield ...
De Loera, J, Vergne, M, BALDONI, MARIA
openaire   +6 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Flow-Based Synthesis of Reactive Tests for Discrete Decision-Making Systems With Temporal Logic Specifications

IEEE Open Journal of Control Systems
Designing tests for autonomous systems is challenging due to their complexity. This work proposes a flow-based approach for reactive test synthesis from temporal logic specifications, enabling the synthesis of test environments consisting of static and ...
Josefine B. Graebener, Apurva S. Badithela, Denizalp Goktas, Wyatt Ubellacker, Eric V. Mazumdar, Aaron D. Ames, Richard M. Murray   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Temporal Flows in Temporal Networks [PDF]

Journal of Computer and System Sciences, 2017
We introduce temporal flows on temporal networks, i.e., networks the links of which exist only at certain moments of time. Such networks are ephemeral in the sense that no link exists after some time. Our flow model is new and differs from the "flows over time" model, also called "dynamic flows" in the literature.
Akrida, Eleni C., Czyzowicz, Jurek, Gąsieniec, Leszek, Kuszner, Łukasz, Spirakis, Paul G.   +4 more
openaire   +10 more sources