Results 51 to 60 of about 74,842 (266)
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Flow characteristics in flow networks [PDF]
A flow network is a system of mutually intersecting holes in a plate or an assembly of plates. The flow at each intersection is characterized by a collision of two flow streams, resulting in complex flow patterns through the downstream holes. In the case of multiple intersections, the flow is periodically disrupted at each succeeding intersection, thus
Lee, C. P. +3 more
openaire +2 more sources
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Les Houches lectures on flow networks in biology
Flows are essential to transport resources over large distances. As soon as diffusion becomes time-limiting, flows are needed. Flows are key for the function of multiple human organs, from the blood vasculature to the lungs, the digestive tract, the ...
Swarnavo Basu, Karen Alim
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Novel Routing Algorithm for the Acceleration of Flow Scheduling in Time-Sensitive Networks
IEEE Time-Sensitive Networking (TSN) Task Group specifies a series of standards such as 802.1Qbv for enhancing the management of time-critical flows in real-time networks.
Jheng-Yu Huang +2 more
doaj +1 more source
At the heart of time-series forecasting (TSF) lies a fundamental challenge: how can models efficiently and effectively capture long-range temporal dependencies across ever-growing sequences? While deep learning has brought notable progress, conventional architectures often face a trade-off between computational complexity and their ability to retain ...
Hongbo Liu, Jia Xu 0004
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Neural Flows in Hopfield Network Approach
In most of the applications involving neural networks, the main problem consists in finding an optimal procedure to reduce the real neuron to simpler models which still express the biological complexity but allow highlighting the main characteristics of ...
Ionescu Carmen +2 more
doaj +1 more source

