When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source
A step-by-step guide for implementation of virtual surgical applications and patient data centralization: practical experience and lessons learned. [PDF]
Coopman R +21 more
europepmc +1 more source
Software switch deployment in SDN-enabled network virtualization environment
Avec la prévalence de logicielisation, virtualisation est devenue une technologie dominante dans des data-centres et clouds. Deux aspects principaux de la logicielisation de réseaux sont Software Defined Network (SDN) et Network Function Virtualization ...
Zhao, Yimeng
core
Charting Endocrine Progenitors Across Species and Organs
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
wiley +1 more source
A Survey on the Computing Continuum and Meta-Operating Systems: Perspectives, Architectures, Outcomes, and Open Challenges. [PDF]
Gkonis PK +6 more
europepmc +1 more source
Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials
Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan +8 more
wiley +1 more source
Hyper-converged space-air-ground integrated low-altitude aerial vehicular networks: Architecture, challenges, and technologies. [PDF]
Zhou H +6 more
europepmc +1 more source
Sustainable Materials Design With Multi‐Modal Artificial Intelligence
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu +8 more
wiley +1 more source
5G Network Slicing: Security Challenges, Attack Vectors, and Mitigation Approaches. [PDF]
Dias J, Pinto P, Santos R, Malta S.
europepmc +1 more source
Two‐Dimensional Triferroics: From Fundamental Couplings to Multifunctional Applications
This graphic summarizes the three main types of currently reported 2D triferroic couplings. From the structural perspective, existing systems can be broadly classified into two categories, which exhibit distinct symmetry features and coupling behaviors. Beyond the lattice difference, a third type involves the interplay among ferroelectricity, magnetism,
Yang Li, Jialin Gong, Zhiqing Li
wiley +1 more source

