Results 51 to 60 of about 96,335 (304)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Health in All Policies (HiAP) governance: Lessons from network governance

open access: yes, 2018
The Health in All Policies (HiAP) approach requires formal and sustained governance structures and mechanisms to ensure that the policies of various non-health sectors maximize positive and minimize negative impacts on population health.
Patrick Kenis   +12 more
core   +1 more source

Effectiveness Network Governance In Making of Special Regional Regulations In Papua Province

open access: yesJournal of Governance and Public Policy, 2018
-Since the implementation of Special Autonomy law, the system of governance of Papua province experiencing changes in terms namely institutional establishment of the Papuan People's Assembly (MRP).
Hamjah Bonso, Suranto Suranto
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

On inclusion and network governance: the democratic disconnect of Dutch energy transitions

open access: yes, 2008
The coordination of policy networks, or network governance, poses threats and opportunities for democracy. Against the norms of liberal democracy, multi-actor partnerships do not fare well: they appear to lack responsiveness, public accountability and ...
Hendriks, C.M., CAROLYN M. HENDRIKS
core   +1 more source

Managing Complexity and Uncertainty in Regional Governance Networks:A Critical Analysis of State Rescaling in England [PDF]

open access: yes, 2014
Network management is viewed as a way of dealing with uncertainty in complex policy networks, but little is known about the types of network management strategies employed by regional actors to manage vertical and horizontal relations.
Stafford, Ian M, Ayres, Sarah A
core   +1 more source

Recognition and Selection of Governance Modes of Private Listed Enterprises Based on BP Neural Network

open access: yes, 2022
Exploring the governance modes of private listed enterprises, this paper divides private listed enterprises into categories of small, medium and large. The governance modes of private listed enterprises can be divided into 9 categories according to two ...
Xu, Lu   +5 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Nilai Strategis Isu Lingkungan dalam Politik Indonesia

open access: yesJSP: Jurnal Ilmu Sosial dan Ilmu Politik, 2007
Environmental issues have been central in the current global potitics and discourse. Furthermore, environment has been set as one of the most important global constitution.
Cornelis Lay
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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