Results 91 to 100 of about 942,568 (264)

Network Regulation Using an Agent [PDF]

open access: yes, 2007
This paper introduces a new regulatory concept: the independent profit-maximising regulatory agent, as a possible model for regulating network industries where complex demand interdependencies, in particular demand complementarities, make traditional ...
McHardy, J., Reynolds, M., Trotter, S.
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Editorial: Improving the sustainability of winegrape vineyards during climate change

open access: yesFrontiers in Plant Science, 2023
Balazs Barna   +3 more
doaj   +1 more source

Larger, diversified and courted : the new triad of local firms of infrastructure in transition ? [PDF]

open access: yes, 2015
International audienceFollowing Jaglin and Verdeil’s argument (2013), this article considers that a certain obsession for energy transition may overlook important transformations of energy systems. A focus on largely understudies local utilities in three
Duque Gomez, Catalina   +2 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Empirical analysis of network effect applicability in Vietnam’s enterprises

open access: yesJournal of International Economics and Management, 2013
By using data from GSO, the paper investigates the possibility of applying network effect in some industries in Vietnam at firm level. The paper confirms that (1) income of consumer, educational qualification of employee and manager, firm’s efficiency ...
Thi Tuong Anh Nguyen
doaj  

A Neural Network Based Shape-from-Shading Measuring Technique for Engineering Industries

open access: yesMeasurement + Control, 2001
A new approach for measuring shape and surface of an object for engineering measurement is proposed. The proposed methodology is a neural network based Shape from Shading (SFS) technique.
Tommy W.S. Chow   +2 more
doaj   +1 more source

Microeconomic Policies in the New Economy [PDF]

open access: yes
Competition policy, Technology policy, Network ...
Stenbacka, Rune
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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