Results 91 to 100 of about 10,294,956 (310)
Technological forecasting & social change, 2019 The “industry 4.0” phenomenon is expected to influence almost every aspect of business value chains, and hence it has been increasingly analyzed by management scholars.
Marcello M. Mariani, M. Borghi
semanticscholar +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Risk spillovers in Chinese production network: A supply-side shock perspective
Humanities & Social Sciences CommunicationsHighly interconnected production network exists in one economy, and it is crucial to investigate how and why supply-side shocks spread across industries via the production network and cause systemic risks in the real sector.
Yuxue Chi +3 more
doaj +1 more source
Resilience Evolution of Dongguan Industrial Network Based on Enterprise Connections
Redai diliCurrently, global uncertainties and instabilities are increasing significantly. Therefore, research on the evolution of urban industrial network resilience is essential for strengthening the ability of urban industries to withstand major events.
Huang Zhuo, Zhao Miaoxi
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
SystemsAs global economic competition intensifies, collaborative innovation in strategic emerging industries has become a key factor in promoting economic growth and business development, attracting widespread attention.
Jianbang Shi, Zhenhong Xiao
doaj +1 more source
The global capacity of Belgium’s major cities: Antwerp and Brussels compared
Belgeo, 2003 The paper has two purposes: (i) to outline a methodology for systematically measuring economic relations between the world’s major cities and (ii) to provide a general assessment of the position of Belgium’s major cities in this global urban network.
Ben Derudder, Peter J. Taylor
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source