Results 61 to 70 of about 7,041,420 (238)

Towards an Effective Intrusion Detection Model Using Focal Loss Variational Autoencoder for Internet of Things (IoT)

Sensors, 2022
As the range of security attacks increases across diverse network applications, intrusion detection systems are of central interest. Such detection systems are more crucial for the Internet of Things (IoT) due to the voluminous and sensitive data it ...
Shapla Khanam, Ismail Ahmedy, Mohd Yamani Idna Idris, Mohamed Hisham Jaward   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Evolving discrete-valued anomaly detectors for a network intrusion detection system using negative selection

, 2006
Network intrusion detection is the problem of detecting unauthorised use of, or access to, computer systems over a network. One approach is anomaly detection, where deviations from a model of normal network activity are reported.
Powers, Simon T., He, Jun
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Network intrusion detection system using supervised learning paradigm

Scientific African, 2020
Internet has positively changed social, political and economic structures and in many ways obviating geographical boundaries. The enormous contributions of Internet to business transactions coupled with its ease of use has resulted in increased number of
J. Olamantanmi Mebawondu, Olufunso D. Alowolodu, Jacob O. Mebawondu, Adebayo O. Adetunmbi   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

LOGICAL TIME AND SPACE OF THE NETWORK INTRUSION

Studia Universitatis Babes-Bolyai: Series Informatica, 2017
Nowadays, one of the biggest threats for modern computer networks are the cyber attacks. One of the possible ways how to increase the level of computer networks security is a deployment of a network intrusion detection system.
Daniel MIHÁLYI, Ján PERHÁČ, Patrik BÁLINT   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Analysis of Network Intrusion Detection Based on Semi-Supervised and SS-DGM

IEEE Access
The rapid advancement of technology has made network security a hot topic of concern for researchers worldwide. Therefore, to improve the accuracy and real-time response capability of network intrusion detection systems, and to effectively detect and ...
Xiao Yu, Chang Liu, Jie Wang, Chang Liu, Li Tian, Liang Zhou   +5 more
doaj   +1 more source