Results 51 to 60 of about 2,335,375 (238)

What Roles Do Local Governments Play in Chinese Urban Energy Transition?

open access: yesSystems
The energy transition is a common challenge faced by all nations. Cities, as the primary hubs of energy consumption, serve as the “front line” in this energy transition. Existing literature acknowledges the importance of governments in energy transitions,
Ling Liu, Rui Zhou, Fangfang Wang
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Gossip Algorithm based Clock Synchronization Scheme for Smart Grid Applications

open access: yes, 2017
The uprising interest in multi-agent based networked system, and the numerous number of applications in the distributed control of the smart grid leads us to address the problem of time synchronization in the smart grid.
Khandaker, Mohammad Aqib   +4 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Self adaptive method for end-to-end available bandwidth estimation

open access: yesTongxin xuebao, 2008
A low overhead, self adaptive method for end-to-end available bandwidth estimation was proposed. Firstly, on low utilization path, the mathematic equation between the probability that input probe gap increases caused by CT pack-ets and the distribution ...
ZHOU An-fu   +3 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Network Measurement and Performance Analysis at Server Side

open access: yesFuture Internet, 2018
Network performance diagnostics is an important topic that has been studied since the Internet was invented. However, it remains a challenging task, while the network evolves and becomes more and more complicated over time.
Guang-Qian Peng   +2 more
doaj   +1 more source

Cloning of a quantum measurement

open access: yes, 2011
We analyze quantum algorithms for cloning of a quantum measurement. Our aim is to mimic two uses of a device performing an unknown von Neumann measurement with a single use of the device.
Bisio, Alessandro   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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