Results 111 to 120 of about 7,275,430 (297)

Patterns and trends of drug abuse in Summit and Stark Counties, Ohio : a report prepared for the Ohio Substance Abuse Monitoring (OSAM) Network

Semiannual; Electronic coverage as of Sept. 26, 2006: June 1999/Jan. 2000-; Description based on: June 1999/Jan. 2000 issue; title from cover of PDF (viewed Sept.
Ohio Substance Abuse Monitoring Network.
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Behavioral responses of migratory caribou to semi-permeable roads in Arctic Alaska

Scientific Reports
Migration conveys many benefits to species, ecosystems, and people but relies upon connected landscapes. Anthropogenic development can present barriers for migrants, but many barriers are semi-permeable, allowing unhindered or delayed passage.
Timothy J. Fullman, Kyle Joly, David D. Gustine, Matthew D. Cameron   +3 more
doaj   +1 more source

Detecting Malicious Devices in IPSEC Traffic with IPv4 Steganography

Applied Sciences
This study investigates the application of steganography for enhancing network security by detecting and promptly eliminating malicious packets to prevent flooding and consequent denial of service attacks while also identifying malicious equipment.
Gabriel Jekateryńczuk, Damian Jankowski, René Veyland, Zbigniew Piotrowski   +3 more
doaj   +1 more source

Network Architecture and Mutual Monitoring in Public Goods Experiments [PDF]

Recent experiments show that public goods can be provided at high levels when mutual monitoring and costly punishment are allowed. All these experiments, however, study monitoring and punishment in a setting where all agents can monitor and punish each ...
Schotter, Andrew, Carpenter, Jeffrey P., Kariv, Shachar   +2 more
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Ambient Lakes Monitoring Network: Panel 1; Volume 1 of 2

, 2008
The New Jersey Department of Environmental Protection (NJDEP) initiated a renewed ambient lake monitoring network in 2005. This renewed initiative was undertaken by Water Monitoring & Standards' (WM&S) Bureau of Freshwater & Biological Monitoring (BFBM).

core   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source