Results 51 to 60 of about 30,701 (217)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Network Monitoring in the age of the Cloud [PDF]
, 2010 Network virtualization plays a relevant role in provisioning an Infrastructure as a Service (IaaS), implementing the fabric that interconnects virtual components. We identify the standard protocol IEEE802.1Q, that describes Virtual LAN (VLAN) functionalities, as a cornerstone in this architecture.
openaire +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Self-monitoring in social networks [PDF]
International Journal of Intelligent Information and Database Systems, 2012 Web 2.0 has changed the technological landscape of the internet computing world today. The shift from traditional web which is also known as Web 1.0 is forced by the growing need for more efficient information sharing, collaboration, and business processes.
Amin Anjomshoaa +4 more
openaire +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Gesture Recognition Based on CNN and DCGAN for Calculation and Text Output
IEEE Access, 2019 In the past few years, with the continuous improvement of hardware conditions, deep learning had performed well in solving many problems, such as visual recognition, speech recognition, and natural language processing.
Wei Fang +3 more
doaj +1 more source
On Soil Carbon Monitoring Networks [PDF]
, 2014 The design of a Soil Monitoring Network (SMN) poses numerous scientific challenges, especially for the assessment of national or continental areas. The task is particularly challenging because soil carbon content and stocks are driven by controlling factors of disparate origins and scales.
Arrouays, Dominique +11 more
openaire +4 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
An Efficient Scheme for Aggregation and Presentation of Network Performance in Distributed Brokering Systems [PDF]
Journal of Systemics, Cybernetics and Informatics, 2003 The Internet is presently being used to support increasingly complex interaction models as a result of more and more applications, services and frameworks becoming network centric.
Gurhan Gunduz +2 more
doaj