Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Service-Aware Hierarchical Fog–Cloud Resource Mappingfor e-Health with Enhanced-Kernel SVM
Fog–cloud-based hierarchical task-scheduling methods are embracing significant challenges to support e-Health applications due to the large number of users, high task diversity, and harsher service-level requirements.
Alaa AlZailaa +3 more
doaj +1 more source
Telecommunications Network Planning and Maintenance
Telecommunications network operators are on a constant challenge to provide new services which require ubiquitous broadband access. In an attempt to do so, they are faced with many problems such as the network coverage or providing the guaranteed Quality
Zorzano Mier, Francisco Javier +3 more
core
BackgroundThe large scale deployment of Electric Road Systems (ERS) is a necessary and viable choice for reaching the emission reduction targets in the road-bound heavy freight sector.
Yang, Can,, Gidofalvi, Gyözö,
core
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Research Trends in Wireless Visual Sensor Networks When Exploiting Prioritization
The development of wireless sensor networks for control and monitoring functions has created a vibrant investigation scenario, where many critical topics, such as communication efficiency and energy consumption, have been investigated in the past few ...
Daniel G. Costa +3 more
doaj +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Intelligent Handover Management in Ultra-Dense 5G Networks: A Deep Q-Learning-Based Prediction Model
Handover optimization is problematic in ultra-dense 5G networks because of the extremely high number of users and base stations. Unlike other methods, classical optimization approaches are not suitable for such technologies due to their complexity.
Nirant Dekate +6 more
doaj +1 more source
Multi-Objective Topology Planning for Microwave-Based Wireless Backhaul Networks
Wireless backhaul networks provide vital infrastructure support for large public and private networks, and their efficient design is essential for smoothly handling the rapid growth of the Internet traffic.
Yongcheng Li +5 more
doaj +1 more source
Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li +10 more
wiley +1 more source

