Results 91 to 100 of about 19,754,425 (354)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Discussion of Evolution of Carrier IP Network to SDN

Dianxin kexue, 2014
Software defined networking（SDN）presents a new network architecture of future network,which is adaptable to the innovation of network technologies and applications and transforming the traditional networks.The issues facing the current service provider ...
Xiaoming He, Hui Ji, Dongfeng Mao, Hong Tang   +3 more
doaj  

RFID‐Based Enhanced Resource Optimization for 5G/6G Network Applications

Engineering Reports
In the rapidly evolving landscape of 5G/6G networks, efficient resource optimization is critical to addressing the escalating demands for high‐speed, low‐latency, and energy‐efficient communication.
Stella N. Arinze, Augustine O. Nwajana
doaj   +1 more source

Performance analysis of energy efficient improved LEACH protocol in IoT networks

, 2022
Surbhi Bhatia, Ankit Kumar, Adarsh Kumar, Asma Alshuhail   +3 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Characterizing the topology dynamics in mobile ad hoc networks:modeling and analyzing techniques using the queuing theory

Tongxin xuebao, 2011
A new modeling parameter named link broken rate（LBR） was proposed so as to characterize the topology dy-namics.On the basis of the definition of the network dynamic characteristics parameter LBR,the expectations of the time interval between the links ...
QIN Guang-cheng1, YANG Pan-long2, TIAN Chang2, CHEN Qiang3, YIN Hao3   +4 more
doaj  

Studying Semi-TCP and Its Application in Marine Internet

Future Internet, 2018
TCP protocol has good performance on the Internet, but its performance is significantly reduced when it is applied to Marine Internet (MI). How to improve the performance of TCP protocol in Marine Internet has become an important research topic.
Liang Zhou, Sheng-Ming Jiang, Chen-Lin Xiong   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Social network analysis in business and management research: A bibliometric analysis of the research trend and performance from 2001 to 2020 [PDF]

, 2022
Adhe Rizky Anugerah, Prafajar Suksessanno Muttaqin, Wahyu Trinarningsih   +2 more
openalex   +1 more source