Results 101 to 110 of about 4,413,107 (338)

Analyzing the Network Response Time and Load Balancing [PDF]

This paper describes the network response time which represent a significant indicator for network performance and how load balancing can improve the network performance.response time, load balancing, throughput, network ...
Madalina MLAK
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Introduction: Performing networks, networks of performance

, 2007
PUBLISHED
openaire   +1 more source

Network Performance : A Monography

, 1999
This paper presents the intermediary results of a monography that attempts to study the link between networking and company performance. The case analysed concerns a network within the metal industry in the Languedoc- Roussillon (south of France) region.
Guibert, Nathalie, Giordano-Spring, Sophie, Eggrickx, Ariel, Dupuy, Yves   +3 more
openaire   +2 more sources

Scenario-based performance analysis of routing protocols for mobile ad-hoc networks [PDF]

, 1999
Per Johansson, Tony Larsson, Nicklas Hedman, Bartosz Mielczarek, Mikael Degermark   +4 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Review for "A compounding-model comprising back propagation neural network and genetic algorithm for performance prediction of bio-based lubricant blending with functional additives"

, 2020
Andrés E. Ciolino
openalex   +1 more source

A Comprehensive Survey on the Performance Analysis of Underwater Wireless Sensor Networks (UWSN) Routing Protocols [PDF]

, 2019
Tariq Mahmood, Khalil ur, Faheem Akhtar, Saqib Ali, Fawaz Mahiuob, Sher Muhammad Daudpota   +5 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source