Results 191 to 200 of about 19,754,425 (354)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Using a dynamic arithmetic optimization approach to improve ridgelet neural network performance in remote sensing scene classification. [PDF]

Sci Rep
Zhang H, Chen J, Xie H, Bagi K.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Brownian motion data augmentation: a method to push neural network performance on nanopore sensors. [PDF]

Bioinformatics
Kipen J, Jaldén J.
europepmc   +1 more source

Cuckoo-PC: An Evolutionary Synchronization-Aware Placement of SDN Controllers for Optimizing the Network Performance in WSNs. [PDF]

Sensors (Basel), 2020
Tahmasebi S, Safi M, Zolfi S, Maghsoudi MR, Faragardi HR, Fotouhi H.   +5 more
europepmc   +1 more source

Prediction of roadheaders' performance using artificial neural network approaches (MLP and KOSFM)

, 2015
Arash Ebrahimabadi, Mohammad Azimipour, Ali Bahreini   +2 more
openalex   +1 more source

An Architecture for High Performance Network Analysis [PDF]

, 2001
Degioanni, L., Risso, Fulvio Giovanni Ottavio   +1 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Impact of rescanning and normalization on convolutional neural network performance in multi-center, whole-slide classification of prostate cancer. [PDF]

Sci Rep, 2020
Swiderska-Chadaj Z, de Bel T, Blanchet L, Baidoshvili A, Vossen D, van der Laak J, Litjens G.   +6 more
europepmc   +1 more source

Spectrum Sensing Performance in Cognitive Radio Networks With Multiple Primary Users

, 2015
António Furtado, Luis Irio, Rodolfo Oliveira, Luís Bernardo, Rui Dinis   +4 more
openalex   +2 more sources