Results 81 to 90 of about 4,413,107 (338)

Discussion of Evolution of Carrier IP Network to SDN

open access: yesDianxin kexue, 2014
Software defined networking(SDN)presents a new network architecture of future network,which is adaptable to the innovation of network technologies and applications and transforming the traditional networks.The issues facing the current service provider ...
Xiaoming He   +3 more
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

RFID‐Based Enhanced Resource Optimization for 5G/6G Network Applications

open access: yesEngineering Reports
In the rapidly evolving landscape of 5G/6G networks, efficient resource optimization is critical to addressing the escalating demands for high‐speed, low‐latency, and energy‐efficient communication.
Stella N. Arinze, Augustine O. Nwajana
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Characterizing the topology dynamics in mobile ad hoc networks:modeling and analyzing techniques using the queuing theory

open access: yesTongxin xuebao, 2011
A new modeling parameter named link broken rate(LBR) was proposed so as to characterize the topology dy-namics.On the basis of the definition of the network dynamic characteristics parameter LBR,the expectations of the time interval between the links ...
QIN Guang-cheng1   +4 more
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Studying Semi-TCP and Its Application in Marine Internet

open access: yesFuture Internet, 2018
TCP protocol has good performance on the Internet, but its performance is significantly reduced when it is applied to Marine Internet (MI). How to improve the performance of TCP protocol in Marine Internet has become an important research topic.
Liang Zhou   +2 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

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