Results 281 to 290 of about 7,014,814 (396)

Prediction of the targets of the main components in blood after oral administration ofXanthii Fructus: a network pharmacology study

, 2018
Yanshuang Zhuang, Kunming Qin, Bing Yang, Xiao Liu, Baochang Cai, Hao Cai   +5 more
openalex   +2 more sources

Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice

Advanced Science, EarlyView.
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu, Jin‐Yin Huang, Xing‐Zhe Xu, Ji‐Yu Sun, Dan‐Ni Zou, Jia‐Yao Zhang, Chen Chi, Qi Zhang, Wei‐Cai Liu   +8 more
wiley   +1 more source

Integrative network pharmacology and experimental validation of anti-inflammatory triterpenoids from hawthorn leaves. [PDF]

Sci Rep
Liu Z, Liu J.
europepmc   +1 more source

Simultaneous clustering analysis with molecular docking in network pharmacology for type 2 antidiabetic compounds

, 2018
Nur Azizah Komara Rifai, Farit Mochamad Afendi, I Made Sumertajaya   +2 more
openalex   +2 more sources

In Situ Proliferating Peptide Nanoparticle Augments Multi‐Target Intervention of Secondary Brain Damage Following Subarachnoid Hemorrhage

Advanced Science, EarlyView.
This work designs an in situ proliferating peptide nanoparticle as a flexible resolution that modulates the neuro‐glia unit to enable enhanced multi‐target combinational therapy for secondary brain damage following subarachnoid hemorrhage. Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered ...
Yibin Zhang, Peisen Yao, Fuxiang Chen, Shufa Zheng, Xuegang Niu, Haojie Wang, Yuanxiang Lin, Bin Gao, Dezhi Kang   +8 more
wiley   +1 more source

Study on the mechanism of no. 8 burn ointment in burn treatment based on network pharmacology and experimental verification. [PDF]

Front Pharmacol
Qiu L, Xing D, Zhu Y, Zhuang Z, Sun Y, Gong P, Chen X.   +6 more
europepmc   +1 more source

Network pharmacology: an important breakthrough in traditional Chinese medicine research

, 2018
JinWei Yuan, Jian Hao, Dan Chen
openalex   +1 more source

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

Advanced Science, EarlyView.
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu, Ze‐Yu Cai, Qing‐Le Li, Tao Zhang, Xiang‐Yu Chu, Chang Wang, Qing‐Yi Zhang, Rong Qi   +7 more
wiley   +1 more source

The Antidiabetic Mechanisms of Cinnamon Extract: Insights from Network Pharmacology, Gut Microbiota, and Metabolites. [PDF]

Curr Issues Mol Biol
Wang R, Yang K, Liu X, Zhang Y, Chen Y, Wang N, Yu L, Liu S, Hu Y, Qin B.   +9 more
europepmc   +1 more source