Results 231 to 240 of about 32,401,733 (254)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

AmoebaNet: An SDN-enabled network service for big data science

open access: yesJournal of Network and Computer Applications, 2018
Data transfer is now an essential function for science discoveries, particularly within big data environments. To support data transfer for big data science, there is a need for high performance, scalable, end-to-end, and programmable networks that ...
Seo-Young Noh, Liang Zhang, Eric Pouyoul
exaly   +1 more source

WILDLIFE TOURISM, SCIENCE AND ACTOR NETWORK THEORY [PDF]

open access: yesAnnals of Tourism Research, 2009
Wildlife tourism is an important component of tourism worldwide. However, for many species little is known about the possible impacts from tourist-wildlife interactions.
David Newsome   +2 more
exaly   +1 more source
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Contributions of modern network science to the cognitive sciences: revisiting research spirals of representation and process

Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2020
Nichol Castro, Cynthia S Q Siew
exaly  

Network science and sustainable performance of family businesses in tourism

Journal of Family Business Management, 2022
Rodolfo Baggio, Marco VALERI
exaly  

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