Results 51 to 60 of about 17,864 (295)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Enabling Smart Home with 5G Network Slicing [PDF]

, 2019
In addition to mobile phones 5G mobile networks will have to support billion IoT devices and applications. To achieve this objective 5G relies in the network slicing concept which is not yet fully understood.
Dzogovic, Bruno, Noll, Josef, Feng, Boning, Santos, Bernardo, Do, van Thanh, Do, Thuan Van   +5 more
core   +2 more sources

Deployment Options of 5G Network Slicing for Smart Healthcare [PDF]

, 2022
Network slicing enables the creation of multiple logical independent networks on physical networking infrastructure. Network slice deployment in a Fifth Generation (5G) mobile network can be classified as vertical and horizontal slicing.
Liyanage, Madhusanka, Siriwardhana, Yushan, De Silva, Rakshitha, Ylianttila, Mika, Samarasinghe, Tharaka   +4 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Resource Allocation in an Open RAN System Using Network Slicing [PDF]

, 2022
The next radio access network (RAN) generation, open RAN (O-RAN), aims to enable more flexibility and openness, including efficient service slicing, and to lower the operational costs in 5G and beyond wireless networks.
Alcaraz López, Onel Luis, Parsaeefard, Saeedeh, Shah-Mansouri, Vahid, Motalleb, Mojdeh Karbalaee   +3 more
core   +1 more source

Resource Allocation for Network Slicing in Mobile Networks [PDF]

IEEE Access, 2020
This paper provides a survey of resource allocation for network slicing. We focus on two classes of existing solutions: ( $i$ ) reservation-based approaches, which allocate resources on a reservation basis, and ( $ii$ ) share-based approaches, which allocate resources based on static overall shares associated to individual slices.
Albert Banchs, Gustavo de Veciana, Vincenzo Sciancalepore, Xavier Costa-Pérez   +3 more
openaire   +4 more sources

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Analysis of Access Strategies Impact on Infrastructure Provider’s Revenue in Case of Network Slicing

Современные информационные технологии и IT-образование, 2021
The article analyses the Network slicing concept and its features associated with the implementation of this technology in 5G networks. By network slicing, the authors mean the simultaneous use of a resource owned by an infrastructure provider by several
Lyubov Lapshenkova, Faina Moskaleva, Yuliya Gaidamaka   +2 more
doaj   +1 more source