Results 231 to 240 of about 735,266 (340)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Security of ADS-B and Remote ID Systems: Cyberattacks, Detection Techniques, and Countermeasures. [PDF]

Sensors (Basel)
Shi Q, Caleb TD, Shao S, Kaabouch N.
europepmc   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

Atten-LTC-Enhanced MoE Model for Agent Trajectory Prediction in Autonomous Driving. [PDF]

Sensors (Basel)
Jiang S, Wang R, Ding R, Ye Q, Liu W.
europepmc   +1 more source

Self-Regulating Cars: Automating Traffic Control in Free Flow Road Networks [PDF]

Ankit Bhardwaj, Rohail Asim, Sachin Chauhan, Yasir Zaki, Lakshminarayanan Subramanian   +4 more
openalex   +1 more source

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Advanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo   +7 more
wiley   +1 more source

AI-driven routing pipeline in software-defined networks using DQL: a mini review. [PDF]

Front Artif Intell
Goteti D, Reddy VK.
europepmc   +1 more source

Optimal Route Guidance and Model Predictive Control of Network-wide Traffic Emission

, 2019
Deepak INGOLE, Guilhem Mariotte, Ludovic Leclercq   +2 more
openalex   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Improved energy efficient load balanced mobility management RPL protocol for mobile internet of things networks. [PDF]

Sci Rep
Diniesh VC, Palaniswamy B, Murali L, Manikandan N, Ramaswamy K.   +4 more
europepmc   +1 more source