Results 161 to 170 of about 9,977,043 (295)

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Protocol for Energy-Efficiency in Networked Control Systems Based on WSN. [PDF]

open access: yesSensors (Basel), 2018
Palma JM   +6 more
europepmc   +1 more source

Modeling and Control of Networked Control Systems with Bounded Delay and Packet Disordering

open access: yes, 2010
In this paper, modeling and stabilization of networked control systems are discussed. Considering the existence of packet disordering in information transmission, a new mathematical model is proposed to describe the dynamical characteristics of networked
Li JN(李金娜)   +3 more
core  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Output Tracking-based H(infinity) Control of Networked Control Systems with Packet Disordering

open access: yes, 2010
This paper is concerned with H(infinity) output tracking control of networked control systems with packet disordering. Considering random and bounded delay and packet disordering, a mathematical model of networked control systems is proposed by ...
Dang XD(党向东)   +3 more
core  

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