Results 31 to 40 of about 189 (186)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Tripartite evolutionary game in the process of network attack and defense

Telecommunication Systems, 2023
Abstract At present, the confrontation in cyberspace is becoming more and more fierce, and network attacks and defenses have become the main form of confrontation between parties in cyberspace. The maximum benefit can be obtained by using scientific decision-making.
Zigang Chen, Chaochao Fan, Tao Leng, Long Chen 0022, Yuhong Liu 0003, Xiaoyong Li, Dongfeng Yuan   +6 more
openaire   +2 more sources

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Evolutionary prisoner’s dilemma games coevolving on adaptive networks [PDF]

Journal of Complex Networks, 2017
We study a model for switching strategies in the Prisoner's Dilemma game on adaptive networks of player pairings that coevolve as players attempt to maximize their return. We use a node-based strategy model wherein each player follows one strategy at a time (cooperate or defect) across all of its neighbors, changing that strategy and possibly changing ...
Mucha, Peter J., Malik, Nishant, Lee, Hsuan-Wei   +2 more
openaire   +3 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Stability of networked evolutionary games with payoff perturbation

IET Control Theory & Applications
In networked evolutionary games (NEGs), some elements in the payoff matrix of players may change due to environmental factors. In this article, the stability of NEGs with payoff perturbation is studied using the semi‐tensor product (STP) of matrices, and
Ziyun Wang, Xiaoyu Zhao, Shihua Fu
doaj   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Evolutionary Power Control Games in Wireless Networks [PDF]

, 2008
In this paper, we apply evolutionary games to non-cooperative power control in wireless networks. Specifically, we focus our study in a power control in W-CDMA and WIMAX wireless systems. We study competitive power control within a large population of mobiles that interfere with each other through many local interactions.
Altman, Eitan, El-Azouzi, Rachid, Hayel, Yezekael, Tembine, Hamidou   +3 more
openaire   +3 more sources

Evolutionary Game for Mining Pool Selection in Blockchain Networks [PDF]

IEEE Wireless Communications Letters, 2018
Submitted to IEEE Wireless Communication ...
Xiaojun Liu 0005, Wenbo Wang 0004, Dusit Niyato, Narisa Zhao, Ping Wang 0001   +4 more
openaire   +3 more sources

Influence of Scan Strategies in Electron Beam Powder Bed Fusion on Solidification, Microstructure, and High‐Temperature Compressive Properties of γ′‐Strengthened Inconel 738LC

Advanced Engineering Materials, EarlyView.
Experiments and thermophysical simulations were conducted to investigate the electron beam powder bed fusion electron beam (PBF‐EB/M) process for the γ′‐strengthened nickel‐based superalloy Inconel 738LC. The results demonstrate the impact of process‐induced microstructural variations on high‐temperature mechanical behavior, providing a basis for ...
Jan Niklas Petenati, Karthik Kumar Banku, Prasanth Bondi, Ivan Zhirnov, Yangyiwei Yang, Gordon Schmidt, Jürgen Christen, Georg Hasemann, Manja Krüger, Bai‐Xiang Xu, Bilal Gökce, Silja‐Katharina Rittinghaus   +11 more
wiley   +1 more source