Results 151 to 160 of about 480,167 (281)

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Selective neural coding of object, feature, and geometry spatial cues in humans. [PDF]

Hum Brain Mapp, 2022
Ramanoël S, Durteste M, Bizeul A, Ozier-Lafontaine A, Bécu M, Sahel JA, Habas C, Arleo A.   +7 more
europepmc   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Neural coding of multiple motion speeds in visual cortical area MT. [PDF]

Elife
Huang X, Ghimire B, Chakrala AS, Wiesner S.   +3 more
europepmc   +1 more source

Methylphenidate as a causal test of translational and basic neural coding hypotheses. [PDF]

Proc Natl Acad Sci U S A, 2022
Ni AM, Bowes BS, Ruff DA, Cohen MR.
europepmc   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

The Dimensionality of Neural Coding for Cognitive Control Is Gradually Transformed within the Lateral Prefrontal Cortex. [PDF]

J Neurosci
Chiou R, Duncan J, Jefferies E, Lambon Ralph MA.   +3 more
europepmc   +2 more sources

Recent advances in spike-based neural coding for tactile perception. [PDF]

Microsyst Nanoeng
Zhu Z, Chen K, Lin W, Yan H, Liang L, Wang G, Song X, Zhang C, Wang Z.   +8 more
europepmc   +1 more source

Selective enhancement of neural coding in V1 underlies fine-discrimination learning in tree shrew. [PDF]

Curr Biol, 2022
Schumacher JW, McCann MK, Maximov KJ, Fitzpatrick D.   +3 more
europepmc   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source