Results 111 to 120 of about 1,636,946 (287)

Roles of cardiac neural crest cells in cardiovascular development and associated congenital defects-an integrated review

Translational Research in Anatomy
The development of the cardiovascular system is a highly intricate process that encompasses various types of cells and communication pathways. During embryonic development, specific cells differentiate and organize to form complex structures of the heart
Worku Abie Liyew, Fentahun Adane, Amsalu Taye Wondemagegn, Binalfew Tsehay, Yikeber Argachew Deml, Hussen Muhidin Abdu, Zelalem Animaw   +6 more
doaj   +1 more source

Interactive conduction

, 2020
A performance of Interactive Conduction at Wintersound 2020 by the Free Range Orchestra and audience member ...
Herbert, D.
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Bone and Cartilage Conduction

Sound can be transmitted to the inner ear not only through the typical air conduction pathway but also through other pathways such as bone conduction and cartilage conduction.

core   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Auditory brainstem response anomalies despite normal hearing in a child with Down syndrome: case-based insight

The Egyptian Journal of Otolaryngology
Background Down syndrome (DS) is associated with a spectrum of cognitive and sensory impairments, including a high prevalence of hearing difficulties.
Praveen Prakash, Stefney Carvalho, Swayam Prabhudessai, Suhas Rathod   +3 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

The Longitudinal Impact of Bone Anchored Hearing Aid Adoption on Resting-State Functional Connectivity Using fNIRS: A Multiple Single-Case Experimental Approach

Journal of Otorhinolaryngology, Hearing and Balance Medicine
Background/Objectives: Three types of neuroplasticity that have been reported following hearing aid uptake include: cross-modal reorganization, homologue shifts, and neighbouring region restructuring.
Cassandra Cowan, Amberley V. Ostevik, Kathleen Jones, Thi K. T. Huynh, Alex Gascon, William Hodgetts, Jacqueline Cummine   +6 more
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source