Results 141 to 150 of about 2,093,786 (309)

Roles of cardiac neural crest cells in cardiovascular development and associated congenital defects-an integrated review

Translational Research in Anatomy
The development of the cardiovascular system is a highly intricate process that encompasses various types of cells and communication pathways. During embryonic development, specific cells differentiate and organize to form complex structures of the heart
Worku Abie Liyew, Fentahun Adane, Amsalu Taye Wondemagegn, Binalfew Tsehay, Yikeber Argachew Deml, Hussen Muhidin Abdu, Zelalem Animaw   +6 more
doaj  

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Electrocardiogram-based prediction of conduction disturbances after transcatheter aortic valve replacement with convolutional neural network [PDF]

Yuheng Jia, Yiming Li, Gadeng Luosang, Jianyong Wang, Gang Peng, Xingzhou Pu, Weili Jiang, Wenjian Li, Zhen‐Gang Zhao, Yong Peng, Yuan Feng, Jiafu Wei, Yuanning Xu, Xingbin Liu, Yi Zhang, Mao Chen   +15 more
openalex   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics

Advanced Engineering Materials, EarlyView.
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani, Aditi Singh, Behnam Ashrafi   +2 more
wiley   +1 more source

Monte Carlo Physics-informed neural networks for multiscale heat conduction via phonon Boltzmann transport equation [PDF]

Qingyi Lin, Chuang Zhang, Xuhui Meng, Zhaoli Guo   +3 more
openalex   +1 more source

A Case‐Based Reasoning Approach to Model Manufacturing Constraints for Impact Extrusion

Advanced Engineering Materials, EarlyView.
A hybrid modeling approach is presented that combines constraint‐based process modeling and case‐based reasoning. The model formalizes manufacturing constraints and integrates simulation data to model complex manufacturing processes. The approach supports manufacturability analysis during product design through an adaptive modeling environment.
Kevin Herrmann, Eduard Ortlieb, Hendrik Wester, Paul Christoph Gembarski, Bernd‐Arno Behrens, Roland Lachmayer   +5 more
wiley   +1 more source

Physics Informed Neural Networks for Heat Conduction with Phasechange [PDF]

Bahae-Eddine Madir, Francky Luddens, Corentin Lothodé, Ionut Danaila   +3 more
  +5 more sources