Results 71 to 80 of about 133,932 (295)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Issues Concerning the Mechanisms of Bone Conduction

Audiology Research
Air and bone conduction thresholds are used to differentiate between conductive and sensori-neural hearing losses because bone conduction is thought to bypass the conductive apparatus, directly activating the inner ear.
Miriam Geal-Dor, Cahtia Adelman, Haim Sohmer   +2 more
doaj   +1 more source

Does the type of electrode affect the electromyoneurographic parameters in rats? [PDF]

Acta Cirúrgica Brasileira, 2019
Purpose: To evaluate if the type of electrode (needle vs. surface) affects the electromyoneurography parameters in rats. Methods: Twenty male rats were anesthetized, then compound muscle action potential were recorded using a Neuropack S1 MEB- 9400 ...
Danusa Neves Somensi, Renan Kleber Costa Teixeira, Daniel Haber Feijó, Karine Drumond Loureiro, André Lopes Valente, Luan Teles Ferreira de Carvalho, Faustino Chaves Calvo, Deivid Ramos dos Santos, Rui Sergio Monteiro de Barros   +8 more
doaj   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Evaluation of the Association Among Cerebrospinal Fluid Protein, Inflammatory Markers, and Electromyography in Pediatric Guillain-Barre Syndrome

Haseki Tıp Bülteni
Aim: Previous studies have shown that the cerebrospinal fluid (CSF) protein level correlates with the number of demyelination criteria in electromyography in adult patients with Guillain-Barré syndrome (GBS), which is a potentially life-threatening ...
Dilek Agircan, Ozlem Ethemoglu, Mustafa Calik, Tulin Gesoglu Demir   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

SENSORY REGRESSION TIME FROM SUBARACHNOID BLOCK WITH HYPERBARIC 0.75% BUPIVACAINE IN THE OBESE PATIENT [PDF]

, 1989
The purpose of this study was to determine if obese patients have a different sensory regression time from subarachnoid block than non-obese patients using hyperbaric 0.75% bupivacaine. A quasi-experimental design was used. Twenty patients were separated
Hilton, George Leslie
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The role of neural precursor cells and self assembling peptides in nerve regeneration

Journal of Otolaryngology - Head and Neck Surgery, 2013
Objective Cranial nerve injury involves loss of central neural cells in the brain stem and surrounding support matrix, leading to severe functional impairment.
Xiao Zhao, Gordon S Yao, Yang Liu, Jian Wang, Kajana Satkunendrarajah, Michael Fehlings   +5 more
doaj   +1 more source

A Real-Time Dual-Microphone Speech Enhancement Algorithm Assisted by Bone Conduction Sensor

Sensors, 2020
The quality and intelligibility of the speech are usually impaired by the interference of background noise when using internet voice calls. To solve this problem in the context of wearable smart devices, this paper introduces a dual-microphone, bone ...
Yi Zhou, Yufan Chen, Yongbao Ma, Hongqing Liu   +3 more
doaj   +1 more source