Results 71 to 80 of about 1,636,946 (287)

Analysis of the efficacy and safety of spinal cord stimulation in the treatment of high-risk diabetic foot

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Objective To evaluate the efficacy and safety of spinal cord stimulation (SCS) in the treatment of high-risk diabetic foot. Methods From January 2023 to May 2024, 25 patients with high-risk diabetic foot who underwent SCS were admitted to Tianjin Huanhu ...
CHEN Xiao-chen   +4 more
doaj   +1 more source

Complementarity of spike- and rate-based dynamics of neural systems [PDF]

open access: yes, 2012
Relationships between spiking-neuron and rate-based approaches to the dynamics of neural assemblies are explored by analyzing a model system that can be treated by both methods, with the rate-based method further averaged over multiple neurons to give a ...
P A Robinson   +11 more
core   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Evaluation of the Association Among Cerebrospinal Fluid Protein, Inflammatory Markers, and Electromyography in Pediatric Guillain-Barre Syndrome

open access: yesHaseki Tıp Bülteni
Aim: Previous studies have shown that the cerebrospinal fluid (CSF) protein level correlates with the number of demyelination criteria in electromyography in adult patients with Guillain-Barré syndrome (GBS), which is a potentially life-threatening ...
Dilek Agircan   +3 more
doaj   +1 more source

The Estimation of surface heat fluxes based on physics-informed neural network

open access: yesKongqi donglixue xuebao
The problem of estimating surface heat fluxes is a typical inverse heat conduction problem. To solve this problem, the estimation of surface heat fluxes based on physics-informed neural network(PINN) is proposed.
Xiancai Zhang   +4 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Multiprocessing neural network simulator

open access: yes, 2013
Over the last few years tremendous progress has been made in neuroscience by employing simulation tools for investigating neural network behaviour.
Kulakov, Anton
core   +1 more source

Issues Concerning the Mechanisms of Bone Conduction

open access: yesAudiology Research
Air and bone conduction thresholds are used to differentiate between conductive and sensori-neural hearing losses because bone conduction is thought to bypass the conductive apparatus, directly activating the inner ear.
Miriam Geal-Dor   +2 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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