Results 111 to 120 of about 97,457 (192)

Dynamic fibronectin assembly and remodeling by leader neural crest cells prevents jamming in collective cell migration. [PDF]

Elife, 2023
Martinson WD, McLennan R, Teddy JM, McKinney MC, Davidson LA, Baker RE, Byrne HM, Kulesa PM, Maini PK.   +8 more
europepmc   +1 more source

Selectivity Filter Dynamics Define Ion Conductance and Selectivity Differences in CNG and HCN Channels

Advanced Science, EarlyView.
Cyclic nucleotide‐gated (CNG) and hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels share substantial sequence and structural similarity but differ markedly in ion conductance and K+ selectivity. Microsecond‐scale atomistic MD simulations qualitatively reproduced the conductance differences observed in single‐channel recordings and ...
Haoran Liu, Klaus Benndorf, Yessenbek K. Aldakul, Han Sun   +3 more
wiley   +1 more source

Loss of SPECC1L in cranial neural crest cells results in increased hedgehog signaling and frontonasal dysplasia. [PDF]

Front Physiol
Tran AJ, Hufft-Martinez BM, Thalman DN, Maili L, McKinney SA, Goering JP, Trainor PA, Saadi I.   +7 more
europepmc   +1 more source

Development of an osteosarcoma model with MYCN amplification and TP53 mutation in hiPS cell-derived neural crest cells. [PDF]

Cancer Sci, 2023
Mukae K, Takenobu H, Endo Y, Haruta M, Shi T, Satoh S, Ohira M, Funato M, Toguchida J, Osafune K, Nakahata T, Kanda H, Kamijo T.   +12 more
europepmc   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

Dynamic and non-uniform expression of key transcription factors provides insights into the emergence of neural crest cells at the neural plate border. [PDF]

Development
Montequin A, LaBonne C.
europepmc   +1 more source

Regulation of Oct4 in stem cells and neural crest cells. [PDF]

Birth Defects Res, 2022
Patel I, Parchem RJ.
europepmc   +1 more source

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

Advanced Science, EarlyView.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi, Di Tang, Johan Malmström, Yasaman Karami, Hamed Khakzad   +4 more
wiley   +1 more source

hPSC-derived sacral neural crest cells restore erectile function in pelvic ganglia injury. [PDF]

Stem Cell Res Ther
Yang T, Liu W, Wu Y, Wang X, Lei T, Tang Q, Zhang Y, Wang H, Zhou Y, Song W.   +9 more
europepmc   +1 more source

In skeletal muscle and neural crest cells, SMCHD1 regulates biological pathways relevant for Bosma syndrome and facioscapulohumeral dystrophy phenotype. [PDF]

Nucleic Acids Res, 2023
Laberthonnière C, Delourme M, Chevalier R, Dion C, Ganne B, Hirst D, Caron L, Perrin P, Adélaïde J, Chaffanet M, Xue S, Nguyen K, Reversade B, Déjardin J, Baudot A, Robin JD, Magdinier F.   +16 more
europepmc   +1 more source