Results 201 to 210 of about 4,418,871 (285)

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Quantitative live imaging reveals PRICKLE1 controls junctional neural tube morphogenesis independent of Planar Cell Polarity. [PDF]

Nat Commun
Wang JX, Alvarez YD, Tan SZ, Ranie SN, Stehbens SJ, White MD.   +5 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Pharmacokinetic Prediction of Repurposed Drugs for PDAC Using Artificial Intelligence. [PDF]

ACS Omega
Pragya P, Singh S, Balasubramaniam B, Agastinose Ronickom JF.   +3 more
europepmc   +1 more source

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

Advanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang, Yundong Li, Xin Wang, Yaning Hou, Wei Deng, Meng Zheng, Yan Zou, Bingyang Shi   +7 more
wiley   +1 more source

Recurrent DNA break clusters drive replication-stress-induced copy number variants and genome diversification. [PDF]

Nat Commun
Corazzi L, Ing A, Benito E, Cosenza MR, Hasenfeld P, Weber T, Marx AJM, Ionasz VS, Trausch N, Benedetto S, Di Muzio G, Ding B, Berlanda J, Giaisi M, Claudino N, Höfer T, Korbel JO, Wei PC.   +17 more
europepmc   +1 more source

Localized Temperature Monitoring in Mouse Brain during Light Delivery via a Non‐Planar Tapered Fiber‐Integrated µRTD Sensor

Advanced Materials, EarlyView.
We report a multifunctional tapered optical fiber integrating a conformal micro‐resistance temperature detector (µRTD) for local, real‐time thermometry during optical stimulation. The platform combines light‐delivery and temperature sensing within a minimally invasive footprint, enabling detection of sub‐degree cortical heating under representative ...
Antonio Balena, Marco Bianco, Barbara Spagnolo, Muhammad Fayyaz Kashif, Alberto Bramati, Massimo De Vittorio, Ferruccio Pisanello   +6 more
wiley   +1 more source

TNF-α and IFN-γ impair neural oscillations and induce neurodegeneration by microglial nitric oxide, metabolic and oxidative stress. [PDF]

J Neuroinflammation
Malorny N, Chausse B, Khodaie B, Elgez A, Söder L, Lewen A, Egorov AV, Kann O.   +7 more
europepmc   +1 more source

Self‐Powered Flexible Triboelectric‐Gated Ion‐Gel Transistor for Neuromorphic Tactile Sensing and Human Activity Recognition

Advanced Materials, EarlyView.
A fully flexible ion‐gel‐gated graphene‐channel transistor driven by a triboelectric nanogenerator enables self‐powered tactile sensing and synaptic learning. Mimicking spike‐rate‐dependent plasticity, the device exhibits frequency‐selective potentiation and depression, supporting rate‐coded neuromorphic computation even under flex.
Hanseong Cho, Seoyeon Park, Youngmin Lee, Sejoon Lee   +3 more
wiley   +1 more source

A different MAPK, ERK5 plays a critical role in cell specification and differentiation. [PDF]

Biochem Biophys Rep
Li J, Hou X, Li X, Ji S.
europepmc   +1 more source