Results 111 to 120 of about 219,698 (314)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
State estimation for discrete-time neural networks with Markov-mode-dependent lower and upper bounds on the distributed delays [PDF]
, 2012 Copyright @ 2012 Springer VerlagThis paper is concerned with the state estimation problem for a new class of discrete-time neural networks with Markovian jumping parameters and mixed time-delays.
Liu, Y, Liu, X, Wang, Z
core +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
General fuzzy min-max neural network for clustering and classification [PDF]
, 2000 This paper describes a general fuzzy min-max (GFMM) neural network which is a generalization and extension of the fuzzy min-max clustering and classification algorithms of Simpson (1992, 1993).
Gabrys, Bogdan, Bargiela, Andrzej
core +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Using neural nets to generate and improve computer graphic procedures [PDF]
, 1992 Image compression using neural networks in the past has focused on just reducing the number of bytes that had to be stored even thought the bytes had no meaning.
Wenzel, Brent C.
core
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Equilibrium analysis of cellular neural networks [PDF]
, 2004 Cellular neural networks are dynamical systems, described by a large set of coupled nonlinear differential equations. The equilibrium point analysis is an important step for understanding the global dynamics and for providing design rules. We yield a set
Checco, P. +3 more
core +1 more source
Neural networks utilization in the video game industry
Вестник университетаThe scope of the video game industry and the use of neural networks in it have been studied. The impact of this technology on the computer games development process has been analyzed, the efficiency of its application in this area noted.
V. V. Godin +3 more
doaj +1 more source