Results 111 to 120 of about 6,298,151 (304)

Neurogenesis Mediated by γ-Aminobutyric Acid and Glutamate Signaling

Journal of Pharmacological Sciences, 2009
.: In this review, we will summarize our ongoing studies on the functionality of both γ-aminobutyric acid (GABA) and glutamate receptors expressed by undifferentiated neural progenitor cells isolated from embryonic rodent brains. Cells were cultured with
Noritaka Nakamichi, Takeshi Takarada, Yukio Yoneda   +2 more
doaj   +1 more source

Programmed cell death in type II neuroblast lineages is required for central complex development in the Drosophila brain [PDF]

, 2012
Background: The number of neurons generated by neural stem cells is dependent upon the regulation of cell proliferation and by programmed cell death.
Heinrich Reichert, Reichert, Heinrich, Yanrui Jiang, Reichert Heinrich, Jiang Yanrui, Jiang, Yanrui, Jiang Y, Reichert H   +7 more
core   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors

Nature Communications, 2016
Molecular mechanisms that control the division of neural progenitor cells are only partially understood. Here the authors show that Diaph3 is critical for spindle checkpoint activity in cortical progenitor cells as the loss of Diaph3 leads to apoptosis ...
Devid Damiani, André M. Goffinet, Arthur Alberts, Fadel Tissir   +3 more
doaj   +1 more source

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

Cell Reports, 2019
Summary: The molecular basis of the earliest neuronal changes that lead to Alzheimer’s disease (AD) is unclear. Here, we analyze neural cells derived from sporadic AD (SAD), APOE4 gene-edited and control induced pluripotent stem cells (iPSCs). We observe
Katharina Meyer, Heather M. Feldman, Tao Lu, Derek Drake, Elaine T. Lim, King-Hwa Ling, Nicholas A. Bishop, Ying Pan, Jinsoo Seo, Yuan-Ta Lin, Susan C. Su, George M. Church, Li-Huei Tsai, Bruce A. Yankner   +13 more
doaj   +1 more source

A two-step strategy for neuronal differentiation in vitro of human dental follicle cells [PDF]

, 2012
Human dental follicle cells (DFCs) derived from wisdom teeth are precursor cells for cementoblasts. In this study, we recognized that naive DFCs express constitutively the early neural cell marker b-IIItubulin.
Völlner, Florian
core   +1 more source

Magnetoelectric BaTiO3/CoFe2O4 Thin‐Film Meshes for Neuronal Differentiation

Advanced Science, EarlyView.
We engineer an epitaxial BaTiO3/CoFe2O4 magnetoelectric mesh that overcomes boundary‐induced mechanical clamping. Progressively reducing the mechanical constraint, from substrate‐clamped to PDMS‐transferred and ultimately freestanding, enhances magnetic‐to‐electric transduction and strengthens magnetoelectric coupling.
Mathieu Mirjolet, Hao Ye, Abderrahim Lahlahi Attalhaoui, Donghoon Kim, Vitaly Pustovalov, Elric Zhang, Marc Tudela‐Pi, Bastian Gebauer, Juan Bautista Carda Castelló, Anton Guimerà‐Brunet, Josep Puigmartí‐Luis, Xiang‐Zhong Chen, Minsoo Kim, Salvador Pané   +13 more
wiley   +1 more source

Functional Glutamate Signaling in Neural Progenitor Cells

YAKUGAKU ZASSHI, 2011
In this review, we have summarized our recent studies on the functionality of ionotropic (iGluR) and metabotropic (mGluR) glutamate receptors expressed by undifferentiated neural progenitor cells (NPC) isolated from embryonic rat and mouse brains.
openaire   +3 more sources

Highly Sensitive Spatial Host‐Microbiome Transcriptomics in FFPE Tissues via Iterative Hydrogel Expansion

Advanced Science, EarlyView.
Ex‐spRandom is a spatial transcriptomics platform that synergizes random‐primed chemistry with iterative hydrogel expansion. By physically decrowding the dense FFPE matrix, this scalable technology shatters the traditional resolution‐sensitivity barrier.
Shunji Zhang, Mengyuan Wang, Jiaye Chen, Yuyi Zhu, Bin Zhu, Ziye Xu, Yuan Liao, Yongcheng Wang   +7 more
wiley   +1 more source

Dual function of Sox1 in telencephalic progenitor cells

, 2007
The transcription factor, Sox1 has been implicated in the maintenance of neural progenitor cell status, but accumulating evidence suggests that this is only part of its function.
Kazanis, I.
core   +2 more sources