Results 211 to 220 of about 8,729,056 (252)

Metabolic‐Redox Remodeling of Inflammatory Synovium by Mannose‐Modified Selenium Nanoparticles for Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
Elevated GLUT1‐driven glycolysis and disrupted selenoprotein‐dependent redox homeostasis drive osteoarthritic progression. Intra‐articular mannose‐modified selenium nanoparticles (M‐SeNPs) selectively target hypermetabolic synovial cells to reprogram aberrant glycolysis and restore endogenous antioxidant defenses.
Yu‐Qing Zou   +15 more
wiley   +1 more source

Lattice Disorder in CuI Enables Filament‐Free Transparent Memristors

open access: yesAdvanced Science, EarlyView.
Transparent Cu1‐xAgxI thin‐film memristors rely on internal ion transport to produce reversible resistive‐switching effects. Direct elemental characterizations observe obvious Cu and Ag redistribution driven by applied bias, proving mobile ions drive the device's resistive‐switching responses.
Yuzhao Ouyang   +13 more
wiley   +1 more source

A Dual‐Functional Nanoplatform Targeting the dsDNA–cGAS Axis to Mitigate Disc Degeneration and Aberrant Innervation

open access: yesAdvanced Science, EarlyView.
RU@PEI‐ZIF integrates dsDNA scavenging with local cGAS inhibition to suppress the dsDNA–cGAS–STING/Netrin‐1 axis in intervertebral disc degeneration. By attenuating nucleus pulposus cell senescence, inflammatory and matrix‐catabolic responses, and pathological sensory innervation, this dual‐functional nanoplatform preserves disc integrity and reduces ...
Zhaojun He   +12 more
wiley   +1 more source

Improved Skills for Predicting Sub‐Seasonal to Seasonal Global Sea Surface Temperature

open access: yesAdvanced Science, EarlyView.
Addressing the critical Sub‐seasonal to Seasonal predictability gap, this study presents CAS‐Canglong, a novel deep learning framework. By leveraging 3D Swin‐Transformers to capture long‐range ocean interactions, the model demonstrates superior skill over traditional GCMs.
Longhao Wang   +6 more
wiley   +1 more source

An Environmental Stable Ionogel‐Based Smart Glove System for Integrated Underwater Communication and Safety Warning

open access: yesAdvanced Science, EarlyView.
This study develops a smart glove by integrating a P(BZMA‐co‐HEA)/IL ionogel with a reconfigurable FPCB for underwater communication and real‐time safety warning. The network‐constrained ionic soft‐space regulation strategy enables mechanical reliability, environmental stability, and sensing adaptability, while the modular FPCB sensor array simplifies ...
Xiaoqin Li   +8 more
wiley   +1 more source

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