Results 241 to 250 of about 215,731 (353)

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

c-Myc and FOXO3a-The Everlasting Decision Between Neural Regeneration and Degeneration. [PDF]

Int J Mol Sci
Khaitin AM, Guzenko VV, Bachurin SS, Demyanenko SV.   +3 more
europepmc   +1 more source

Facilitation and delay sensitivity of auditory cortex neurons in CF-FM bats, Rhinolopus rouxi and Pteronotus p. parnellii [PDF]

, 1991
O'Neill, W. E., Radtke-Schuller, Susanne, Schuller, Gerd   +2 more
core   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Spinal cord injury and inflammatory mediators: Role in "fire barrier" formation and potential for neural regeneration. [PDF]

Neural Regen Res
Zhou M, Xu Z, Zhong H, Ning G, Feng S.
europepmc   +1 more source

Conductive Scaffolding for Neural Tissue Regeneration: 3D Bridging with Two-Photon Fabrication [PDF]

Vladimir Osipov, Aminah Jawed, Petro Lutsyk, David J. Webb, Antonio Fratini   +4 more
openalex  

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Graphene-based materials: an innovative approach for neural regeneration and spinal cord injury repair. [PDF]

RSC Adv
Yari-Ilkhchi A, Hamidi N, Mahkam M, Ebrahimi-Kalan A.   +3 more
europepmc   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

[Effect of composite graphene-protein hydrogels on neural regeneration after spinal cord injury in rats]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhang Z, Fan Z, Wang X, Zhu Z.
europepmc   +1 more source